Oxaliplatin
- Generic Name
- Oxaliplatin
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C8H14N2O4Pt
- CAS Number
- 61825-94-3
- Unique Ingredient Identifier
- 04ZR38536J
- Background
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride moieties. Due to this chemic...
- Indication
Oxaliplatin, in combination with infusional fluorouracil and leucovorin, is indicated for the treatment of advanced colorectal cancer and adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the primary tumor.
- Associated Conditions
- Advanced Colorectal Cancer, Stage III Colon Cancer
- Associated Therapies
- -
Irinotecan With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-12-19
- Lead Sponsor
- Sanofi
- Registration Number
- NCT00012389
- Locations
- 🇺🇸
University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, United States
🇺🇸Northwestern Medical Faculty Foundation, Chicago, Illinois, United States
🇺🇸Hematology Oncology Consultants Inc, Columbus, Ohio, United States
Combination Chemotherapy in Treating Patients With Advanced Cancer That is Metastatic or Cannot Be Removed By Surgery
- Conditions
- Interventions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-12-11
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 50
- Registration Number
- NCT00043121
- Locations
- 🇺🇸
University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States
Oxaliplatin and Paclitaxel in Treating Patients With Metastatic or Unresectable Cancer
- Conditions
- Locations
- 🇺🇸
Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States
Gefitinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Colorectal Cancer
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-05-15
- Lead Sponsor
- Stanford University
- Registration Number
- NCT00025142
- Locations
- 🇺🇸
Stanford Cancer Center at Stanford University Medical Center, Stanford, California, United States
Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
- Conditions
- Interventions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-05-03
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 560
- Registration Number
- NCT00005036
- Locations
- 🇺🇸
North Central Cancer Treatment Group, Rochester, Minnesota, United States
Combination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent, or Metastatic Colorectal Cancer
- Conditions
- Interventions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-05-03
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 26
- Registration Number
- NCT00006015
- Locations
- 🇺🇸
Vermont Cancer Center, Burlington, Vermont, United States
🇺🇸CCOP - Southern Nevada Cancer Research Foundation, Las Vegas, Nevada, United States
🇺🇸Norris Cotton Cancer Center, Lebanon, New Hampshire, United States
Erlotinib and Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-06-24
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Registration Number
- NCT00049101
- Locations
- 🇺🇸
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-06-20
- Lead Sponsor
- National Cancer Institute (NCI)
- Registration Number
- NCT00039611
- Locations
- 🇺🇸
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
🇺🇸St. Vincent Hospital and Health Center, Billings, Montana, United States
🇺🇸Mayo Clinic, Jacksonville, Florida, United States
Combination Chemotherapy in Treating Patients With Colorectal Cancer
- Conditions
- Locations
- 🇫🇷
Hopital Saint-Louis, Paris, France
🇫🇷Centre de Lutte Contre le Cancer Georges-Francois Leclerc, Dijon, France
🇫🇷Centre Hospital Regional Universitaire de Limoges, Limoges, France
Comparing Two Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer
- Conditions
- Locations
- 🇫🇷
Hopital Saint Antoine, Paris, France
Drug Development Updates
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