• A Phase 2 trial of KN026 plus docetaxel shows a 76.4% objective response rate in HER2+ metastatic breast cancer patients.
• The combination therapy resulted in a median progression-free survival of 27.7 months, indicating a potential first-line treatment option.
• The study reports a manageable safety profile, with no deaths attributable to KN026 or docetaxel, suggesting a favorable cardiac safety profile.
• A Phase 3 trial is planned to further evaluate the efficacy and safety of KN026 in combination with HB1801 for HER2+ metastatic breast cancer.