MedPath

Depatuxizumab

Generic Name
Depatuxizumab
Drug Type
Biotech
CAS Number
1471999-69-5
Unique Ingredient Identifier
W984C353CG
Background

Depatuxizumab has been used in trials studying the treatment and diagnostic of Adenocarcinoma and Advanced Solid Tumors.

KN026 Plus Docetaxel Shows Promise in HER2+ Metastatic Breast Cancer

• A Phase 2 trial of KN026 plus docetaxel shows a 76.4% objective response rate in HER2+ metastatic breast cancer patients. • The combination therapy resulted in a median progression-free survival of 27.7 months, indicating a potential first-line treatment option. • The study reports a manageable safety profile, with no deaths attributable to KN026 or docetaxel, suggesting a favorable cardiac safety profile. • A Phase 3 trial is planned to further evaluate the efficacy and safety of KN026 in combination with HB1801 for HER2+ metastatic breast cancer.
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