MedPath

Probucol

Generic Name
Probucol
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C31H48O2S2
CAS Number
23288-49-5
Unique Ingredient Identifier
P3CTH044XJ
Background

A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).

Indication

Used to lower LDL and HDL cholesterol.

Associated Conditions
-
Associated Therapies
-

Pharmacokinetics Study for Probucol

Phase 4
Completed
Conditions
Healthy
Interventions
First Posted Date
2009-10-23
Last Posted Date
2022-03-04
Lead Sponsor
Korea Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
30
Registration Number
NCT01000467
Locations
🇰🇷

Seoul national univeristy, Seoul, Korea, Republic of

Study of Cilostazol and Probucol to Assess Their Effects on Atherosclerosis Related Biomarker

Phase 4
Completed
Conditions
Type 2 Diabetes Mellitus
Arteriosclerosis Obliterans
Interventions
Drug: Cilostazol+Probucol
Other: Control Group
Drug: Probucol
Drug: Cilostazol
First Posted Date
2009-01-16
Last Posted Date
2010-04-22
Lead Sponsor
Otsuka Beijing Research Institute
Target Recruit Count
200
Registration Number
NCT00823849
Locations
🇨🇳

Peking University First Hospital, Beijing, China

Probucol Combined With Valsartan in Reducing Proteinuria in Diabetes Nephropathy

Not Applicable
Conditions
Type 2 Diabetes Mellitus
Nephropathy
Interventions
First Posted Date
2008-04-09
Last Posted Date
2016-08-24
Lead Sponsor
Guangdong Provincial People's Hospital
Target Recruit Count
170
Registration Number
NCT00655330
Locations
🇨🇳

Guangdong General Hospital, Guangzhou, Guangdong, China

Safety and Pharmacokinetics of Probucol and Cilostazol

Phase 4
Completed
Conditions
Healthy
Interventions
First Posted Date
2007-10-26
Last Posted Date
2022-03-04
Lead Sponsor
Korea Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
32
Registration Number
NCT00549978
Locations
🇰🇷

Clinical Trial Center, Seoul National University Hospital, Seoul, Korea, Republic of

A Study of the Antioxidant Probucol Combined With Valsartan in Patients With IgA Nephropathy

Phase 4
Completed
Conditions
Glomerulonephritis
IGA Nephropathy
Interventions
First Posted Date
2007-01-24
Last Posted Date
2013-08-28
Lead Sponsor
Guangdong Provincial People's Hospital
Target Recruit Count
75
Registration Number
NCT00426348
Locations
🇨🇳

Guangdong General Hospital, Guangzhou, Guangdong, China

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