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Iron

Generic Name
Iron
Brand Names
Citranatal B-calm Kit, Citranatal Harmony, Concept Ob, Ferralet 90, Natafort, Vitafol-one
Drug Type
Small Molecule
Chemical Formula
Fe
CAS Number
7439-89-6
Unique Ingredient Identifier
E1UOL152H7

Overview

A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Iron is used to build up the blood in anemia.

Indication

Used in preventing and treating iron-deficiency anemia.

Associated Conditions

  • Anemia
  • Iron Deficiency (ID)
  • Iron Deficiency Anemia (IDA)
  • Restless Legs Syndrome (RLS)
  • Concomitant myelosuppressive chemotherapy

Research Report

Published: Jul 24, 2025

Iron (DB01592): A Comprehensive Monograph on its Pharmacology, Clinical Utility, and Safety Profile

Introduction to Iron: An Essential Element

Iron stands as a fundamental element not only in the Earth's crust but also within the intricate biological machinery of virtually all living organisms. Its unique chemical properties allow it to participate in a vast array of metabolic processes, making it indispensable for life. However, this same chemical reactivity renders it potentially toxic, necessitating a complex and tightly regulated system of absorption, transport, and storage within the body. This monograph provides a comprehensive examination of iron, identified by DrugBank ID DB01592, from its basic chemical profile to its complex pharmacology, diverse clinical applications, and extensive safety considerations. It synthesizes current knowledge to offer a detailed resource on iron's dual role as an essential nutrient and a critical therapeutic agent.

Chemical and Physical Profile

Elemental iron is a small molecule drug with the chemical symbol Fe.[1] It is unequivocally identified in scientific and regulatory databases by its Chemical Abstracts Service (CAS) Number 7439-89-6.[1] As a fundamental element, its molecular properties are defined by its atomic characteristics.

Continue reading the full research report

Clinical Trials

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Title
Posted
Study ID
Phase
Status
Sponsor
2024/09/19
Not Applicable
Completed
Central Park Medical College
2024/08/15
Phase 4
Completed
Centre Hospitalier Hassan II - Fès
2024/07/23
Phase 1
Completed
2024/07/22
Phase 1
Recruiting
2024/07/18
Phase 2
Withdrawn
Mateusz Opyrchal
2024/07/05
Phase 2
Not yet recruiting
The Second Hospital of Nanjing Medical University
2024/06/20
Phase 1
Recruiting
2024/05/31
Not Applicable
Active, not recruiting
Akram Medical Complex
2024/05/30
Phase 3
Not yet recruiting
2024/05/23
Phase 4
Not yet recruiting

FDA Drug Approvals

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Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
Everett Laboratories, Inc.
0642-0092
ORAL
27 mg in 1 1
4/18/2012
MARTIN EKWEALOR PHARMACEUTICALS, INC.
58607-112
ORAL
150 mg in 1 1
2/20/2014
Everett Laboratories, Inc.
0642-0070
ORAL
29 mg in 1 1
9/1/2021
Nephro-Tech, Inc.
59528-4456
ORAL
66 mg in 1 1
7/14/2021
Acella Pharmaceuticals, LLC
42192-343
ORAL
28 mg in 1 1
9/11/2018
MISSION PHARMACAL COMPANY
0178-0799
ORAL
28 mg in 1 1
6/3/2011
Bryant Ranch Prepack
63629-3545
ORAL
27 mg in 1 1
7/17/2014
MISSION PHARMACAL COMPANY
0178-0798
ORAL
30 mg in 1 1
1/18/2012
CarWin Pharmaceutical Associates, LLC
15370-250
ORAL
31 mg in 1 1
12/23/2019
Everett Laboratories, Inc.
0642-0120
ORAL
29 mg in 1 1
7/21/2014

EMA Drug Approvals

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Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

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NMPA Drug Approvals

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Approval Number
Drug Type
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Approval Date
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PPB Drug Approvals

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TGA Drug Approvals

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Status
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Health Canada Drug Approvals

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Approved Product
Company
DIN
Dosage Form
Strength
Market Date
LIPOTOX
bio active canada ltd.
02233643
Liquid - Oral
12 X
5/26/1998
FERRUM METALLICUM
seroyal international inc.
02233134
Tablet ,  Liquid ,  Drops ,  Pellet ,  Granules ,  Globules - Oral
1 X
4/6/1998
FERRUM SIDERIUM D8(D10 D12 D15 D20) DPS
weleda ag heilmittelbetriebe
02088452
Drops - Oral
8 D / ML
12/31/1995
FERO GRAD FILMTAB
ABBOTT LABORATORIES, LIMITED
00038857
Tablet (Extended-Release) - Oral
105 MG
12/31/1961
TRIOGENE FOR
produits francais labs inc.
00166219
Powder - Oral
209.82 MG / 30 G
12/31/1930
NUTRILITE DOUBLE X PACK
amway of canada, ltd.
00763047
Tablet - Oral
3.3 MG / PCK
12/31/1988
MULTIPLE VITAMINS AND MINERALS
d.c. labs limited
01922572
Tablet - Oral
15 MG
12/31/1976
MULTIVITAMINS W MINERALS EXTRA STRENGTH
watkins incorporated
00240931
Capsule - Oral
18 MG
12/31/1972
HOMEOPATHIC MEDICINE (S137) DPS 30C
total health centre
02071525
Drops - Oral
30 C / ML
12/31/1994
HEMAREXIN TAB
lab bio chimique inc.,division of technilab pharma inc.
00514764
Tablet - Oral
5 MG
12/17/1997

CIMA AEMPS Drug Approvals

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Company
Registration Number
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Prescription Type
Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

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Saudi SFDA Drug Approvals

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License Number
Dosage Form
Strength
Approval Date
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Malaysia NPRA Drug Approvals

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UK EMC Drug Information

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MA Number
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Authorization Date
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