MedPath

MK-0752

Generic Name
MK-0752
Drug Type
Small Molecule
Chemical Formula
C21H21ClF2O4S
CAS Number
471905-41-6
Unique Ingredient Identifier
9JD9B4S53T
Background

Mk 0752 is under investigation in clinical trial NCT00572182 (MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer).

Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049)

Phase 1
Completed
Conditions
Advanced Cancer
Interventions
First Posted Date
2011-02-14
Last Posted Date
2015-08-27
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
65
Registration Number
NCT01295632

A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)

Phase 1
Terminated
Conditions
Neoplasms Malignant
Interventions
First Posted Date
2010-11-19
Last Posted Date
2018-08-16
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
47
Registration Number
NCT01243762

A Clinical Study to Determine Biomarkers of Response to a Gamma Secretase Inhibitor

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2008-12-08
Last Posted Date
2016-06-17
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
30
Registration Number
NCT00803894

Study Of MK-0752 In Combination With Tamoxifen Or Letrozole to Treat Early Stage Breast Cancer

Phase 4
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2008-09-22
Last Posted Date
2019-09-04
Lead Sponsor
Loyola University
Target Recruit Count
22
Registration Number
NCT00756717
Locations
🇺🇸

Loyola Univeristy Medical Center, Cardinal Bernardin Cancer Center, Maywood, Illinois, United States

MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer

Phase 1
Terminated
Conditions
Brain and Central Nervous System Tumors
First Posted Date
2007-12-12
Last Posted Date
2012-03-06
Lead Sponsor
Pediatric Brain Tumor Consortium
Target Recruit Count
33
Registration Number
NCT00572182
Locations
🇺🇸

Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Children's National Medical Center, Washington, District of Columbia, United States

🇺🇸

Children's Memorial Hospital - Chicago, Chicago, Illinois, United States

and more 9 locations
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