Chloroquine
- Generic Name
- Chloroquine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C18H26ClN3
- CAS Number
- 54-05-7
- Unique Ingredient Identifier
- 886U3H6UFF
- Background
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a number of other c...
- Indication
Chloroquine is indicated to treat infections of P. vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also used to treat extraintestinal amebiasis.
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- Associated Conditions
- Discoid Lupus Erythematosus (DLE), Extraintestinal Amebiasis, Malaria, Polymorphic Light Eruption (PLE), Porphyria Cutanea Tarda, Rheumatoid Arthritis, Sarcoidosis, Acute, uncomplicated Malaria
- Associated Therapies
- -
Relationships Between the Use of Antimalarial Drugs in Pregnancy and Plasmodium Falciparum Resistance
- Conditions
- First Posted Date
- 2005-09-01
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 700
- Registration Number
- NCT00140517
- Locations
- 🇧🇫
Centre Medicale Paul VI, Ouagadougou, Burkina Faso
Chloroquine and Amodiaquine for Treatment of Malaria in Children
- Conditions
- First Posted Date
- 2005-08-30
- Last Posted Date
- 2008-04-08
- Lead Sponsor
- Bandim Health Project
- Target Recruit Count
- 720
- Registration Number
- NCT00137514
- Locations
- 🇬🇼
Bandim Health Project, Apartado 861, Bissau, Guinea-Bissau
Influence of Chloroquine on HIV Viral Load Among Pregnant Women in Uganda
- Conditions
- First Posted Date
- 2005-08-22
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 2548
- Registration Number
- NCT00132535
- Locations
- 🇺🇬
Uganda AIDS Commission, Kampala, Uganda
Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women
- First Posted Date
- 2005-08-19
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 900
- Registration Number
- NCT00131703
Antimalarial Drug Resistance in Mali
- Conditions
- First Posted Date
- 2005-08-09
- Last Posted Date
- 2006-08-16
- Lead Sponsor
- Centers for Disease Control and Prevention
- Target Recruit Count
- 1011
- Registration Number
- NCT00127998
- Locations
- 🇲🇱
Koro Health Center, Koro, Mali
🇲🇱Faladje Missionary Dispensary, Faladje, Mali
🇲🇱Pongono Community Health Center, Pongono, Mali
Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparum
- Conditions
- First Posted Date
- 2004-05-14
- Last Posted Date
- 2011-04-26
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 14
- Registration Number
- NCT00082563
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.