Chloroquine
- Generic Name
- Chloroquine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C18H26ClN3
- CAS Number
- 54-05-7
- Unique Ingredient Identifier
- 886U3H6UFF
- Background
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a number of other c...
- Indication
Chloroquine is indicated to treat infections of P. vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also used to treat extraintestinal amebiasis.
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- Associated Conditions
- Discoid Lupus Erythematosus (DLE), Extraintestinal Amebiasis, Malaria, Polymorphic Light Eruption (PLE), Porphyria Cutanea Tarda, Rheumatoid Arthritis, Sarcoidosis, Acute, uncomplicated Malaria
- Associated Therapies
- -
Chloroquine and Post Malaria Anaemia Study
- First Posted Date
- 2007-05-16
- Last Posted Date
- 2014-10-13
- Lead Sponsor
- Medical Research Council Unit, The Gambia
- Target Recruit Count
- 96
- Registration Number
- NCT00473837
Atheroma Reduction With Chloroquine in Patients With the Metabolic Syndrome (ARCH-MS)
- Conditions
- Interventions
- First Posted Date
- 2007-04-03
- Last Posted Date
- 2021-12-15
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 357
- Registration Number
- NCT00455403
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
Safety and Efficacy of Chloroquine Associated With Dehydroepiandrosterone Sulphate to Treat Uncomplicated Falciparum Malaria
- Conditions
- First Posted Date
- 2007-03-01
- Last Posted Date
- 2007-03-01
- Lead Sponsor
- Université Victor Segalen Bordeaux 2
- Target Recruit Count
- 200
- Registration Number
- NCT00442403
- Locations
- 🇨🇲
Institute of Medical Research and study of Medicinal Plants, Medical Research Center, Yaounde, Cameroon
Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria
- First Posted Date
- 2007-02-27
- Last Posted Date
- 2021-11-02
- Lead Sponsor
- Medicines for Malaria Venture
- Target Recruit Count
- 456
- Registration Number
- NCT00440999
- Locations
- 🇹🇭
MaeLamad District Hospital, Mae Ramat, Tak Province, Thailand
🇹🇭MaeSod General Hospital, Mae Sot, Tak Province, Thailand
🇰🇭Pailin Referral Hospital, Pailin, Pailin Province, Cambodia
Chloroquine and Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Guinea Bissau
- Conditions
- Interventions
- First Posted Date
- 2007-01-24
- Last Posted Date
- 2011-01-04
- Lead Sponsor
- Bandim Health Project
- Target Recruit Count
- 300
- Registration Number
- NCT00426439
- Locations
- 🇬🇼
Bandim Health Project, Apartado 861, Bissau, Guinea-Bissau
CuraChik : A Trial of the Efficacy and Safety of Chloroquine as Therapeutic Treatment of Chikungunya Disease
- Conditions
- First Posted Date
- 2006-10-23
- Last Posted Date
- 2015-08-28
- Lead Sponsor
- Assistance Publique Hopitaux De Marseille
- Registration Number
- NCT00391313
- Locations
- 🇫🇷
Cellule Coordination Nivachik, Saint Pierre, ile de la Reunion, France
Chloroquine Alone or in Combination for Malaria in Children in Malawi
- Conditions
- Interventions
- First Posted Date
- 2006-09-25
- Last Posted Date
- 2014-08-11
- Target Recruit Count
- 640
- Registration Number
- NCT00379821
- Locations
- 🇲🇼
Blantyre Malaria Project - Ndirande Health Centre, Blantyre, Malawi
Investigating the Anti-Human Immunodeficiency Virus (HIV) & Anti-inflammatory Effect of Chloroquine
- First Posted Date
- 2006-03-29
- Last Posted Date
- 2020-06-04
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 13
- Registration Number
- NCT00308620
- Locations
- 🇺🇸
Minnesota ACTU, Minneapolis, Minnesota, United States
Chloroquine for Treatment of Glioblastoma Multiforme
- Conditions
- Locations
- 🇲🇽
National Institute of Neurology and Neurosurgery, Mexico City, Mexico
Impact of Insecticide-treated Curtains on Antimalarial Drug Resistance
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- London School of Hygiene and Tropical Medicine
- Target Recruit Count
- 1035
- Registration Number
- NCT00169078
- Locations
- 🇧🇫
Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Kadiogo, Burkina Faso
Drug Development Updates
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