Pregabalin
- Generic Name
- Pregabalin
- Brand Names
- Lyrica, Pregabalin Accord, Pregabalin Pfizer, Pregabalin Sandoz, Pregabalin Mylan, Pregabalin Zentiva
- Drug Type
- Small Molecule
- Chemical Formula
- C8H17NO2
- CAS Number
- 148553-50-8
- Unique Ingredient Identifier
- 55JG375S6M
- Background
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively defined, there is evidence that pregabalin exerts its effects by bind...
- Indication
Pregabalin is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, fibromyalgia, neuropathic pain associated with spinal cord injury, and as adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older.
- Associated Conditions
- Diabetic Peripheral Neuropathic Pain (DPN), Epilepsies, Fibromyalgia, Generalized Anxiety Disorder, Neuropathic Pain, Partial-Onset Seizures, Peripheral Neuropathic Pain, Peripheral neuropathy, Postherpetic Neuralgia
- Associated Therapies
- -
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
- Conditions
- Interventions
- First Posted Date
- 2024-10-08
- Last Posted Date
- 2024-12-20
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 1100
- Registration Number
- NCT06628908
- Locations
- 🇺🇸
Pinnacle Research Group, LLC, Anniston, Alabama, United States
🇺🇸Synexus Clinical Research US - Birmingham, Birmingham, Alabama, United States
🇺🇸Synexus Clinical Research US - Phoenix Central, Phoenix, Arizona, United States
Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy
- Conditions
- Interventions
- First Posted Date
- 2024-10-01
- Last Posted Date
- 2024-12-10
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 300
- Registration Number
- NCT06619860
- Locations
- 🇺🇸
AMR Fort Myers (The Clinical Study Center), Fort Myers, Florida, United States
🇺🇸Innovation Medical Research Center, Palmetto Bay, Florida, United States
🇺🇸ARSN - NeuroStudies, Decatur, Georgia, United States
SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy.
- First Posted Date
- 2024-09-26
- Last Posted Date
- 2024-09-26
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 190
- Registration Number
- NCT06614322
- Locations
- 🇺🇸
Beth Israel Deaconess Medical Center for Autonomic and Peripheral Nerve Disorders, Boston, Massachusetts, United States
🇺🇸Washington University School of Medicine, St. Louis, Missouri, United States
🇺🇸University of Rochester, Rochester, New York, United States
Improving Perioperative Sleep Disorders
- First Posted Date
- 2024-07-22
- Last Posted Date
- 2024-11-13
- Lead Sponsor
- Mengchang Yang
- Target Recruit Count
- 222
- Registration Number
- NCT06512155
- Locations
- 🇨🇳
Sichuan Provincial People's Hospita, Chengdu, Sichuan, China
The Treatment of Postherpetic Neuralgia in the Head and Face With Superficial Needling Combined With Electroacupuncture
- Conditions
- Interventions
- First Posted Date
- 2024-05-20
- Last Posted Date
- 2024-06-25
- Lead Sponsor
- Zhejiang Chinese Medical University
- Target Recruit Count
- 124
- Registration Number
- NCT06420778
- Locations
- 🇨🇳
Xiaoyu Li, Hangzhou, Zhejiang, China
Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair
- Conditions
- Interventions
- First Posted Date
- 2024-04-16
- Last Posted Date
- 2024-08-23
- Lead Sponsor
- The Catholic University of Korea
- Target Recruit Count
- 76
- Registration Number
- NCT06367998
Comparing Efficiency of Mirogabalin and Pregabalin in Primary TKA
- Conditions
- Interventions
- First Posted Date
- 2024-03-25
- Last Posted Date
- 2024-03-25
- Lead Sponsor
- Thammasat University Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT06328062
- Locations
- 🇹🇭
Thammasat University Hospital, Khlong Luang, Pathum Thani, Thailand
Evaluate the Efficacy and Safety of JMKX000623 in Participants With Diabetic Peripheral Neuropathic Pain
- Conditions
- Interventions
- First Posted Date
- 2024-01-24
- Last Posted Date
- 2024-04-16
- Lead Sponsor
- Jemincare
- Target Recruit Count
- 220
- Registration Number
- NCT06221241
- Locations
- 🇨🇳
Peking University First Hospital, Beijing, Beijing, China
Sleep and Neuropathic Pain - Intervention Study on Pregabalin
- Conditions
- Interventions
- First Posted Date
- 2023-12-05
- Last Posted Date
- 2023-12-05
- Lead Sponsor
- Helsinki University Central Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT06155916
- Locations
- 🇫🇮
Helsinki University Hospital, Department of Neurology, Helsinki, Uusimaa, Finland
🇫🇮Helsinki University Central Hospital, Helsinki, HUS, Finland
A Trial Investigating the Pain-relieving Properties of Lu AG06474 in Healthy Adult Participants
- Conditions
- Interventions
- First Posted Date
- 2023-10-11
- Last Posted Date
- 2024-06-28
- Lead Sponsor
- H. Lundbeck A/S
- Target Recruit Count
- 26
- Registration Number
- NCT06077786
- Locations
- 🇳🇱
Centre for Human Drug Research, Leiden, Netherlands
Drug Development Updates
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