Triclosan
- Generic Name
- Triclosan
- Brand Names
- Dermaprot Triclotrex-B, Ting
- Drug Type
- Small Molecule
- Chemical Formula
- C12H7Cl3O2
- CAS Number
- 3380-34-5
- Unique Ingredient Identifier
- 4NM5039Y5X
- Background
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
- Indication
Triclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. It is also used in health care settings in surgical scrubs and personnel hand washes.
- Associated Conditions
- Acne, Dental Cavity, Dermabrasion, Gingivitis, Plaque, Dental, Abrasions, Bacterial skin infections, Minor burns, Oral infections
- Associated Therapies
- Antibacterial therapy, Antibiotic pre-surgical prophylaxis
Xolair Shows Superior Efficacy Over Oral Immunotherapy in Landmark Food Allergy Trial
• Phase III OUtMATCH study demonstrates Xolair's superior efficacy with 36% of patients tolerating multiple food allergens compared to 19% in the oral immunotherapy group.
• Xolair treatment showed significantly better safety profile with zero serious adverse events, while oral immunotherapy group experienced 30.5% serious adverse events and higher treatment discontinuation rates.
• Follow-up data reveals promising results for post-Xolair food introduction, with 61-70% success rates for milk, egg, and wheat allergens, though lower rates for nuts.
Drug Development Updates
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