Emodepside
- Generic Name
- Emodepside
- Drug Type
- Small Molecule
- Chemical Formula
- C60H90N6O14
- CAS Number
- 155030-63-0
- Unique Ingredient Identifier
- YZ647Y5GC9
- Background
Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the octadepsipeptides, a relatively new class of anthelmintic.
Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections
- Conditions
- Hookworm InfectionTrichuris Trichiura; InfectionAscaris Lumbricoides Infection
- Interventions
- Drug: matching placebo of emodepsideDrug: similar placebo to mebendazole
- First Posted Date
- 2025-01-29
- Last Posted Date
- 2025-02-10
- Lead Sponsor
- Swiss Tropical & Public Health Institute
- Target Recruit Count
- 315
- Registration Number
- NCT06800248
- Locations
- 🇵🇭
University of the Philippines Manila, Manila, Philippines
Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections
- Conditions
- Trichuris Trichiura; InfectionHookworm InfectionAscaris Lumbricoides Infection
- Interventions
- Drug: matching placebo of emodepsideDrug: similar placebo to mebendazole
- First Posted Date
- 2024-12-17
- Last Posted Date
- 2025-02-10
- Lead Sponsor
- Swiss Tropical & Public Health Institute
- Target Recruit Count
- 315
- Registration Number
- NCT06736691
- Locations
- 🇹🇿
Public Health Laboratory - Ivo de Carneri (PHL-IdC), Chake Chake, Tanzania
A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants
- Conditions
- Soil-transmitted Helminth InfectionOnchocerciasis (River Blindness)
- Interventions
- First Posted Date
- 2024-05-14
- Last Posted Date
- 2024-09-27
- Lead Sponsor
- Bayer
- Target Recruit Count
- 40
- Registration Number
- NCT06412926
- Locations
- 🇩🇪
NUVISAN GmbH Neu-Ulm, Neu-Ulm, Bayern, Germany
Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis
- Conditions
- StrongyloidiasisStrongyloides Stercoralis Infection
- Interventions
- First Posted Date
- 2024-04-18
- Last Posted Date
- 2024-11-20
- Lead Sponsor
- Swiss Tropical & Public Health Institute
- Target Recruit Count
- 202
- Registration Number
- NCT06373835
- Locations
- 🇱🇦
Lao Tropical and Public Health Institute, Vientiane, Lao People's Democratic Republic
Efficacy and Safety of Emodepside in Adolescents and Adults Infected With Hookworm
- First Posted Date
- 2022-09-14
- Last Posted Date
- 2023-06-15
- Lead Sponsor
- Jennifer Keiser
- Target Recruit Count
- 320
- Registration Number
- NCT05538767
- Locations
- 🇹🇿
Public Health Laboratory Ivo de Carneri, Chake Chake, Pemba, Tanzania
Emodepside Phase II Trial for Treatment of Onchocerciasis
- Conditions
- Onchocerciasis
- Interventions
- Drug: matching placebo of emodepsideDrug: matching placebo of ivermectin
- First Posted Date
- 2022-01-06
- Last Posted Date
- 2024-03-05
- Lead Sponsor
- Drugs for Neglected Diseases
- Target Recruit Count
- 578
- Registration Number
- NCT05180461
- Locations
- 🇬🇭
University of Health and Allied Services School of Public Health, Hohoe, Volta Region, Ghana
🇨🇩Hôpital général de référence de Masimanimba, Masi-Manimba, Kwilu, Congo, The Democratic Republic of the
🇨🇩Centre de santé de référence de Kimpese, Kimpese, Kongo Central, Congo, The Democratic Republic of the
Efficacy and Safety of Emodepside in Adults Infected With Trichuris Trichiura and Hookworm
- Conditions
- Hookworm InfectionsTrichuris Trichiura; Infection
- Interventions
- First Posted Date
- 2021-08-23
- Last Posted Date
- 2022-05-27
- Lead Sponsor
- Jennifer Keiser
- Target Recruit Count
- 442
- Registration Number
- NCT05017194
- Locations
- 🇹🇿
Public Health Laboratory - Ivo de Carneri, Chake Chake, Tanzania
Relative Bioavailability Study of Emodepside IR-tablets and Solution
- First Posted Date
- 2017-12-26
- Last Posted Date
- 2020-03-09
- Lead Sponsor
- Drugs for Neglected Diseases
- Target Recruit Count
- 77
- Registration Number
- NCT03383523
- Locations
- 🇬🇧
Hammersmith Medicines Research (HMR) Limited, London, United Kingdom
First in Man Clinical Trial of Emodepside (BAY 44-4400)
- Conditions
- Healthy Volunteers
- Interventions
- Drug: placebo
- First Posted Date
- 2016-01-22
- Last Posted Date
- 2020-04-13
- Lead Sponsor
- Drugs for Neglected Diseases
- Target Recruit Count
- 79
- Registration Number
- NCT02661178
- Locations
- 🇬🇧
Hammersmith Medicines Research, London, United Kingdom
Drug Development Updates
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