Alclometasone
生产企业：Nycomed us inc, Altana inc，另有 3 家
Alclometasone is a topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses.
Alclometasone is a topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses.
The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A. Alclometasone initially binds the corticosteroid receptor. This complex migrates to the nucleus where it binds to different glucocorticoid response elements on the DNA. This in turn enhances and represses various genes, especially those involved in inflammatory pathways.
用于治疗各种皮肤疾病。
共 1 项相关疾病
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
