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Propranolol

Generic Name
Propranolol
Brand Names
Hemangeol, Hemangiol, Inderal, Innopran
Drug Type
Small Molecule
Chemical Formula
C16H21NO2
CAS Number
525-66-6
Unique Ingredient Identifier
9Y8NXQ24VQ

Overview

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension. Propranolol was granted FDA approval on 13 November 1967.

Background

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension. Propranolol was granted FDA approval on 13 November 1967.

Indication

Propranolol is indicated to treat hypertension. Propranolol is also indicated to treat angina pectoris due to coronary atherosclerosis, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, pheochromocytoma, and proliferating infantile hemangioma.

Associated Conditions

  • Akathisia caused by antipsychotic use
  • Angina Pectoris
  • Atrial Fibrillation
  • Cardiovascular Mortality
  • Essential Tremor
  • Gastroesophageal variceal hemorrhage prophylaxis
  • Hemangiomas
  • Hypertension
  • Migraine
  • Myocardial Infarction
  • Obstructive Hypertrophic Cardiomyopathy
  • Performance Anxiety
  • Pheochromocytoma
  • Proliferating Infantile Hemangioma
  • Supraventricular Arrhythmias
  • Tachyarrhythmia caused by Digitalis intoxication
  • Tachyarrhythmia caused by catecholamine excess
  • Thyroid Crisis
  • Thyrotoxicosis
  • Tremor caused by lithium
  • Ventricular Tachycardia (VT)

FDA Approved Products

Propranolol Hydrochloride
Manufacturer:Proficient Rx LP
Route:ORAL
Strength:60 mg in 1 1
Approved: 2023/02/01
NDC:71205-760
Propranolol Hydrochloride ER
Manufacturer:Blenheim Pharmacal, Inc.
Route:ORAL
Strength:80 mg in 1 1
Approved: 2015/04/09
NDC:10544-286
Propranolol Hydrochloride ER
Manufacturer:ANI Pharmaceuticals, Inc.
Route:ORAL
Strength:60 mg in 1 1
Approved: 2022/06/22
NDC:62559-530
Propranolol Hydrochloride
Manufacturer:Proficient Rx LP
Route:ORAL
Strength:10 mg in 1 1
Approved: 2018/12/01
NDC:71205-185
Propranolol Hydrochloride
Manufacturer:Medical Purchasing Solutions, LLC
Route:INTRAVENOUS
Strength:1 mg in 1 mL
Approved: 2023/05/23
NDC:71872-7096

Singapore Approved Products

NALOL TABLET 40 mg
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:TABLET
Strength:40 mg
Online:Yes
Approved: 1988/06/23
Approval:SIN01978P
PROPANOL TABLET 10 mg
Manufacturer:BEACONS PHARMACEUTICALS PTE. LTD.
Form:TABLET
Strength:10 mg
Online:Yes
Approved: 1988/03/16
Approval:SIN00094P
NALOL TABLET 80 mg
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:TABLET
Strength:80 mg
Online:Yes
Approved: 1994/05/05
Approval:SIN07708P
APO-PROPRANOLOL TABLET 40 mg
Manufacturer:APOTEX INC
Form:TABLET
Strength:40 mg
Online:Yes
Approved: 1988/02/24
Approval:SIN00041P
INPANOL TABLET 40 mg
Manufacturer:PT ACTAVIS INDONESIA
Form:TABLET
Strength:40 mg
Online:Yes
Approved: 1988/02/24
Approval:SIN00075P

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