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Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement . It is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency and prevention of osteoporosis. The most common form is calcium L-threonate, or (2R,3S)-2,3,4-trihydroxy butyric acid calcium . L-threonate is an active metabolite of vitamin C that mediates a stimulatory action on vitamin C uptake . Therapeutic efficacy of calcium threonate in reducing was studied and investigated due to the hypothesis that it may play a role in the mineralization process through its positive action on vitamin C.
Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement . It is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency and prevention of osteoporosis. The most common form is calcium L-threonate, or (2R,3S)-2,3,4-trihydroxy butyric acid calcium . L-threonate is an active metabolite of vitamin C that mediates a stimulatory action on vitamin C uptake . Therapeutic efficacy of calcium threonate in reducing was studied and investigated due to the hypothesis that it may play a role in the mineralization process through its positive action on vitamin C.
Once dissociated to calcium and L-theronic acid, L-threonic acid exhibits significant stimulatory action on vitamin C uptake and prolongs the retention of vitamin C in human T-lymphoma cells . Vitamin C is a marker for osteoblast formation and has been shown to stimulate procollagen and enhance collagen synthesis . Via stimulation of vitamin C uptake, L-threonic acid acts as a metabolite that influences the mineralization process .
No approved therapeutic indications.
每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。
