Tipifarnib

Generic Name
Tipifarnib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C27H22Cl2N4O
CAS Number
192185-72-1
Unique Ingredient Identifier
MAT637500A
Background

Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. It is also called Zarnestra. In June 2005, the FDA issued a Not Approvable Letter for Zarnestra.

Indication

Investigated for use/treatment in colorectal cancer, leukemia (myeloid), pancreatic cancer, and solid tumors.

Associated Conditions
-
Associated Therapies
-

Penn State College of Medicine, Beat Childhood Cancer Research Consortium leading ...

Penn State College of Medicine, Beat Childhood Cancer Research Consortium, and Four Diamonds are launching a clinical trial to test a new drug combination for relapsed and refractory neuroblastoma, involving tipifarnib and naxitamab. The trial aims to improve treatment outcomes for children with neuroblastoma by enhancing the efficacy of immunotherapy.
manilatimes.net
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Kura Oncology to Participate in JMP Securities Hematology and Oncology Summit

Kura Oncology to participate in JMP Securities Hematology and Oncology Summit on Dec 2, 2024. The company is focused on precision medicines for cancer treatment, with ziftomenib as a key drug candidate.
medcitynews.com
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Kura Oncology Gets $330M to Kick Off Global Leukemia Drug Pact With Kyowa Kirin

Kura Oncology secures $330 million from Kyowa Kirin for ziftomenib, a menin inhibitor targeting KMT2A-mutated leukemia, with plans for FDA submission in 2025. The collaboration aims to develop ziftomenib across leukemias and solid tumors, with potential milestone payments up to $1.2 billion.

Kura Oncology Positioned for Growth with Promising Trial Developments and Strong Financials

JMP Securities' Reni Benjamin maintains Buy rating on Kura Oncology (KURA) with $32.00 price target, citing KOMET-001 study results expected in 2025, breakthrough designation for Zifto in NPM1-m AML, strong cash position, and upcoming data presentations.
biospace.com
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Kura Oncology to Report Third Quarter 2024 Financial Results

Kura Oncology to report Q3 2024 financial results on Nov 7, 2024, with a webcast and conference call at 4:30 p.m. ET / 1:30 p.m. PT. The call can be accessed via phone or webcast on the company's website.
quantisnow.com
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Kura Oncology Appoints Michael Vasconcelles, M.D., to Board of Directors

Kura Oncology appoints Michael Vasconcelles, M.D., to its Board of Directors. Dr. Vasconcelles brings over 25 years of oncology drug development experience and leadership. He is currently a Senior Advisor at Frazier Healthcare Partners and has held senior roles at ImmunoGen, Flatiron Health, Unum Therapeutics, Takeda/Millennium, and Genzyme Corporation. Dr. Vasconcelles expressed enthusiasm for Kura's precision oncology approach and its menin inhibitor program for acute leukemias.
stocktitan.net
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Kura Oncology, Inc. Latest Stock News & Market Updates

Kura Oncology (KURA) is a clinical-stage biopharmaceutical company developing precision medicines for cancer, with key candidates like Tipifarnib, Ziftomenib, and KO-2806. Recent achievements include preliminary data from the KOMET-007 trial and securing financing through 2027.
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