Estradiol valerate
- Generic Name
- Estradiol valerate
- Brand Names
- Delestrogen, Natazia
- Drug Type
- Small Molecule
- Chemical Formula
- C23H32O3
- CAS Number
- 979-32-8
- Unique Ingredient Identifier
- OKG364O896
- Background
Estradiol Valerate (also known as E2V) is a pro-drug ester of Estradiol, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects with...
- Indication
Estradiol valerate is commercially available as an intramuscular injection as the product Delestrogen and is indicated for the treatment of moderate to severe vasomotor symptoms and vulvovaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen...
- Associated Conditions
- Advanced Hormone Dependent Prostate Cancer, Heavy Menstrual Bleeding, Hypogonadism, Menopausal Symptoms, Menopause, Menstrual Irregularities, Postmenopausal Osteoporosis, Primary Amenorrhoea, Secondary Amenorrhea, Hypoestrogenism, Moderate Menopausal Vasomotor Symptoms, Moderate menopausal vulvovaginal atrophy, Severe Vasomotor Symptoms Associated With Menopause, Severe menopausal vulvovaginal atrophy
- Associated Therapies
- Hormone Replacement Therapy, Oral Contraceptives
Estradiol's Effect on Brain Volume and Connectivity
- Conditions
- Interventions
- First Posted Date
- 2024-03-15
- Last Posted Date
- 2024-03-15
- Lead Sponsor
- International Research Training Group 2804
- Target Recruit Count
- 32
- Registration Number
- NCT06312033
- Locations
- 🇩🇪
University of Tuebingen; Department of Psychiatry & Psychotherapy, Tuebingen, BW, Germany
Estradiol and Stress Reactivity in Women
- Conditions
- Interventions
- First Posted Date
- 2024-01-12
- Last Posted Date
- 2024-03-08
- Lead Sponsor
- International Research Training Group 2804
- Target Recruit Count
- 74
- Registration Number
- NCT06204016
- Locations
- 🇩🇪
University of Tuebingen; Department of Psychiatry & Psychotherapy, Tuebingen, BW, Germany
Descriptive Analysis of Serum Immunological Markers During an Euploid Frozen Embryo Transfer in a Natural Cycle.
- Conditions
- Interventions
- First Posted Date
- 2022-07-25
- Last Posted Date
- 2023-07-20
- Lead Sponsor
- ART Fertility Clinics LLC
- Target Recruit Count
- 40
- Registration Number
- NCT05473273
- Locations
- 🇦🇪
ART Fertility Clinics LLC, Abu Dhabi, United Arab Emirates
Hormonal Monitoring and Progesterone Adjustment in Frozen Embryo Transfer Cycles
- Conditions
- Interventions
- First Posted Date
- 2022-01-12
- Last Posted Date
- 2024-02-02
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 600
- Registration Number
- NCT05189145
- Locations
- 🇪🇬
Infertility Center, Alexandria, Egypt
Effect of Transgender Therapy on Muscle, Fat and Tissue Receptors
- Conditions
- Interventions
- First Posted Date
- 2020-09-16
- Last Posted Date
- 2024-01-08
- Lead Sponsor
- St. Louis University
- Target Recruit Count
- 4
- Registration Number
- NCT04551144
- Locations
- 🇺🇸
Saint Louis Univeristy, Saint Louis, Missouri, United States
The Outcome of Two Protocols Used to Prepare Endometrium for Frozen Embryo Transfer
- Conditions
- Interventions
- First Posted Date
- 2020-08-10
- Last Posted Date
- 2022-04-27
- Lead Sponsor
- Rahem Fertility Center
- Target Recruit Count
- 112
- Registration Number
- NCT04507022
- Locations
- 🇪🇬
Rahem Fertility Center, Zagazig, Sharkia, Egypt
Endometrial Effects of Sildenafil in Frozen-Thawed Cycles in Women With Thin Endometrium
- Conditions
- Interventions
- First Posted Date
- 2020-02-25
- Last Posted Date
- 2021-08-20
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 100
- Registration Number
- NCT04283435
- Locations
- 🇪🇬
Cairo University, Cairo, Egypt
Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS)
- Conditions
- Interventions
- First Posted Date
- 2019-06-28
- Last Posted Date
- 2021-01-08
- Lead Sponsor
- CRG UZ Brussel
- Registration Number
- NCT04002635
Natural Cycle Versus Hormone Replacement Therapy Cycle for a Frozen-thawed Embryo Transfer in PGT Patients
- Conditions
- Interventions
- First Posted Date
- 2019-06-06
- Last Posted Date
- 2024-10-09
- Lead Sponsor
- CRG UZ Brussel
- Target Recruit Count
- 362
- Registration Number
- NCT03976544
- Locations
- 🇧🇪
Centre for Reproductive Medicine UZ Brussel, Brussels, Belgium
Oestradiol Supplementation in Luteal Long Agonist Fresh In Vitro Fertilization/Intra Cytoplasmic Sperm Injection ( IVF/ICSI) Cycle .
- First Posted Date
- 2019-02-06
- Last Posted Date
- 2019-02-07
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 2
- Registration Number
- NCT03832894
- Locations
- 🇪🇬
Art Unit/ Obatetrics and Gynecology Department, Cairo, Cair0, Egypt
Drug Development Updates
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