MedPath

Alvelestat

Generic Name
Alvelestat
Drug Type
Small Molecule
Chemical Formula
C25H22F3N5O4S
CAS Number
848141-11-7
Unique Ingredient Identifier
6Y5629322X
Background

Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.

AZD9668 Relative Bioavailability

Phase 1
Completed
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
First Posted Date
2009-12-18
Last Posted Date
2010-02-05
Lead Sponsor
AstraZeneca
Target Recruit Count
28
Registration Number
NCT01034982
Locations
🇩🇪

Research Site, Berlin, Germany

Efficacy and Safety of Twice Daily 60mg AZD9668 in COPD for 12 Weeks in Patients on Background Budesonide/Formoterol

Phase 2
Completed
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Drug: Placebo
First Posted Date
2009-12-02
Last Posted Date
2012-08-03
Lead Sponsor
AstraZeneca
Target Recruit Count
615
Registration Number
NCT01023516
Locations
🇸🇰

Research Site, Zilina, Slovakia

A Dose Range Finding Study to Evaluate the Efficacy and Safety of AZD9668 Administered Orally at Three Dose Levels to Patients With Chronic Obstructive Pulmonary Disease (COPD) on Treatment With Tiotropium

Phase 2
Completed
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Drug: AZD9668 Placebo
First Posted Date
2009-07-31
Last Posted Date
2012-08-03
Lead Sponsor
AstraZeneca
Target Recruit Count
838
Registration Number
NCT00949975
Locations
🇺🇦

Research Site, Lugansk, Ukraine

A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis

Phase 2
Completed
Conditions
Bronchiectasis
Interventions
Drug: Placebo
First Posted Date
2008-10-08
Last Posted Date
2012-08-20
Lead Sponsor
AstraZeneca
Target Recruit Count
38
Registration Number
NCT00769119
Locations
🇬🇧

Research Site, New Castle, United Kingdom

A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Cystic Fibrosis

Phase 2
Completed
Conditions
Cystic Fibrosis
Interventions
Drug: AZD9668 Placebo equivalent
First Posted Date
2008-09-23
Last Posted Date
2012-08-20
Lead Sponsor
AstraZeneca
Target Recruit Count
56
Registration Number
NCT00757848
Locations
🇬🇧

Research Site, Liverpool, United Kingdom

A Two Week Study to Assess the Tolerability of AZD9668 in Chronic Obstructive Pulmonary Disease (COPD) Patients

Phase 2
Completed
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Drug: Placebo
First Posted Date
2008-06-23
Last Posted Date
2012-01-26
Lead Sponsor
AstraZeneca
Target Recruit Count
18
Registration Number
NCT00703391
Locations
🇩🇪

Research Site, Berlin, Germany

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