Conjugated estrogens

Generic Name
Conjugated estrogens
Brand Names
Congest, Duavee, Duavive, Premarin, Premphase 28 Day, Prempro 0.625/2.5 28 Day
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
12126-59-9
Unique Ingredient Identifier
IU5QR144QX
Background

The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material. Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.
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Indication

The conjugated estrogens are indicated for several different conditions including:

Associated Conditions
Abnormal Uterine Bleeding, Atrophic Vaginitis, Atrophy of vulva, Kraurosis Vulvae, Menopause, Metastatic Breast Cancer, Moderate to Severe Vasomotor Symptoms, Osteoporosis, Androgen-dependent tumor Advanced Prostate Carcinoma, Hypoestrogenism, Moderate Dyspareunia, Moderate Vulvar and Vaginal Atrophy, Severe Dyspareunia, Severe Vulvar and Vaginal Atrophy
Associated Therapies
Estrogen Replacement Therapy, Palliative Treatment
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Short-Term Hormone Therapy for Menopause Won't Harm Women's Brains

Four years of hormone replacement therapy (HRT) for menopause causes no harm to the brain, even 10 years after stopping, according to a study by Carey Gleason's team at the University of Wisconsin-Madison. Published in PLOS Medicine, the research found no cognitive decline among women who had taken HRT, but also no cognitive benefits, indicating HRT should not be seen as a means to boost neurological health.
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