Glycopyrronium
- Generic Name
- Glycopyrronium
- Brand Names
- Bevespi, Breztri, Cuvposa, Dartisla, Enurev Breezhaler, Glycate, Glyrx, Lonhala, Prevduo, Qbrexza, Robinul, Robinul Forte, Seebri Breezhaler, Sialanar, Tovanor Breezhaler, Ultibro
- Drug Type
- Small Molecule
- Chemical Formula
- C19H28NO3
- CAS Number
- 740028-90-4
- Unique Ingredient Identifier
- A14FB57V1D
- Background
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications. Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of pept...
- Indication
Glycopyrronium formulated as a topical cloth is indicated to treat primary axillary hyperhidrosis in patients ≥9 years, and an inhalational solution is indicated for long term maintenance of airflow obstruction in COPD. A glycopyrronium intravenous and intramuscular injection is indicated in adults and pediatric patients to reduce the volume and acidity of g...
- Associated Conditions
- Airway Obstruction, Chronic Obstructive Pulmonary Disease (COPD), Increased upper airway secretion, Peptic Ulcer, Primary Axillary Hyperhidrosis, Sialorrhea, Cardiac vagal inhibitory reflexes, Cardiac vagal inhibitory reflexes caused by General Surgery, Cardiac vagal inhibitory reflexes caused by Medication, Gastric secretions, Peripheral muscarinic effects
- Associated Therapies
- -
Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting Surgery
- Conditions
- Interventions
- First Posted Date
- 2019-05-07
- Last Posted Date
- 2023-12-27
- Lead Sponsor
- West Virginia University
- Target Recruit Count
- 84
- Registration Number
- NCT03939923
- Locations
- 🇺🇸
WVU Medicine, Morgantown, West Virginia, United States
The Use of Sugammadex in the Critically Ill
- Conditions
- Interventions
- First Posted Date
- 2019-01-03
- Last Posted Date
- 2019-08-21
- Lead Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Target Recruit Count
- 50
- Registration Number
- NCT03791801
- Locations
- 🇨🇦
McGill University Health Center, Montreal, Quebec, Canada
🇨🇦MUHC, Montréal, Quebec, Canada
Intraoperative Video Laryngoscopy as Adjunct for Nerve Monitoring
- Conditions
- Interventions
- First Posted Date
- 2018-11-15
- Last Posted Date
- 2023-10-02
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 125
- Registration Number
- NCT03742141
- Locations
- 🇺🇸
Mount Sinai Beth Israel, New York, New York, United States
🇺🇸Mount Sinai Queens, Long Island City, New York, United States
🇺🇸The Mount Sinai Hospital, New York, New York, United States
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
- Conditions
- Interventions
- First Posted Date
- 2018-07-10
- Last Posted Date
- 2018-08-16
- Lead Sponsor
- B.P. Koirala Institute of Health Sciences
- Target Recruit Count
- 138
- Registration Number
- NCT03580889
- Locations
- 🇳🇵
Dr. BishnuPokharel, Dharān Bāzār, Sunsari, Nepal
Dexmedetomidine and Propofol for Pediatric MRI Sedation
- First Posted Date
- 2018-05-02
- Last Posted Date
- 2020-02-21
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 40
- Registration Number
- NCT03513757
- Locations
- 🇺🇸
Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States
Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn Surgery
- First Posted Date
- 2018-05-01
- Last Posted Date
- 2023-09-28
- Lead Sponsor
- University of Kansas Medical Center
- Target Recruit Count
- 7
- Registration Number
- NCT03513406
- Locations
- 🇺🇸
University of Kansas Medical Center, Kansas City, Kansas, United States
Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2017-11-29
- Last Posted Date
- 2021-01-05
- Lead Sponsor
- Lena Nilsson
- Target Recruit Count
- 150
- Registration Number
- NCT03357393
Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Adult Patients Undergoing Lower Extremity Surgery Under Spinal Anesthesia
- First Posted Date
- 2017-10-26
- Last Posted Date
- 2019-03-14
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 2
- Registration Number
- NCT03322150
- Locations
- 🇰🇷
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of
Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal Anesthesia
- First Posted Date
- 2017-10-26
- Last Posted Date
- 2018-09-24
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 54
- Registration Number
- NCT03322098
- Locations
- 🇰🇷
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of
Sugammadex Versus Neostigmine for Reversal of Rocuronium Neuromuscular
- Conditions
- Interventions
- First Posted Date
- 2017-10-26
- Last Posted Date
- 2021-11-16
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 69
- Registration Number
- NCT03322657
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
Drug Development Updates
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