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Orphenadrine

Generic Name
Orphenadrine
Brand Names
Norgesic, Norgesic Forte, Orfenace, Orphengesic
Drug Type
Small Molecule
Chemical Formula
C18H23NO
CAS Number
83-98-7
Unique Ingredient Identifier
AL805O9OG9
Background

A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

Indication

用于治疗帕金森病和吩噻嗪类药物引起的锥体外系症状,但对迟发性运动障碍无效。用于治疗急性肌骨骼疼痛

Associated Conditions
Back Pain Lower Back, Fever, Menstrual Distress (Dysmenorrhea), Mild pain, Muscle Spasms, Mild Musculoskeletal Disorder, Mild to moderate pain, Moderate Musculoskeletal Disorder, Moderate Pain
Associated Therapies
-

Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery

First Posted Date
2022-06-10
Last Posted Date
2022-06-10
Lead Sponsor
University of Puerto Rico
Target Recruit Count
100
Registration Number
NCT05413902
Locations
🇵🇷

Puerto Rico Medical Center - University District Hospital, San Juan, Puerto Rico

Orphenadrine Versus Baclofen in Treatment of Muscle Cramps in Cirrhotic Patients

Not Applicable
Terminated
Conditions
Cirrhosis
Interventions
First Posted Date
2020-08-12
Last Posted Date
2022-04-29
Lead Sponsor
Mansoura University
Target Recruit Count
5
Registration Number
NCT04509336
Locations
🇪🇬

Tanta University Hospitals, Tanta, Egypt

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Phase 4
Conditions
Ileus
Colon Cancer
Ileus; Mechanical
Constipation Drug Induced
Colon Diverticulosis
Colonic Neoplasms
Pain, Postoperative
Ileus Paralytic
Colonic Diverticulitis
Constipation
Interventions
First Posted Date
2016-11-08
Last Posted Date
2017-03-20
Lead Sponsor
University of Illinois College of Medicine at Peoria
Target Recruit Count
80
Registration Number
NCT02958566
Locations
🇺🇸

Uicomp, Peoria, Illinois, United States

Orphenadrine and Methocarbamol for LBP

Phase 4
Completed
Conditions
Low Back Pain
Interventions
First Posted Date
2016-01-27
Last Posted Date
2018-06-26
Lead Sponsor
Montefiore Medical Center
Target Recruit Count
240
Registration Number
NCT02665286
Locations
🇺🇸

Montefiore Medical Center, Bronx, New York, United States

Study of Orphenadrine' in the Treatment of Muscle Cramps in Patients With Cirrhosis

Phase 3
Recruiting
Conditions
Liver Cirrhosis
Muscle Cramps
Interventions
Drug: Placebo
Drug: orphenadrine
First Posted Date
2015-04-22
Last Posted Date
2019-06-07
Lead Sponsor
Sherief Abd-Elsalam
Target Recruit Count
100
Registration Number
NCT02423395
Locations
🇪🇬

Tanta university hospital, Tanta, Egypt

Patient Preferences, Analgesic Delivery Method and Pain Reduction in Spine Patients

First Posted Date
2010-12-21
Last Posted Date
2020-05-27
Lead Sponsor
Western Galilee Hospital-Nahariya
Registration Number
NCT01263652
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