Follitropin
- Generic Name
- Follitropin
- Brand Names
- Bemfola, Follistim, Gonal F, Gonal-F, Menopur, Ovaleap, Pergoveris, Puregon, GONAL-f, Rekovelle
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 146479-72-3
- Unique Ingredient Identifier
- 2M2GGL7HUP
- Background
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glyco...
- Indication
In women having been diagnosed with primary ovarian failure, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility. In men with hypogonadotrophic hypogonadism, it is used to induce spermatogenesis. Follitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use...
- Associated Conditions
- -
- Associated Therapies
- Assisted Reproductive Technology therapy, Controlled Ovarian Stimulation
Impact of Blastocyst Morphological Development and Blastocoele Re-expansion on Pregnancy Outcome After Using REKOVELLE®
- First Posted Date
- 2018-10-05
- Last Posted Date
- 2023-12-12
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 362
- Registration Number
- NCT03697031
- Locations
- 🇩🇰
Ciconia, VivaNeo (there may be other sites in this country), Højbjerg, Denmark
Study to Assess the Patterns of Use of REKOVELLE® in Naïve Women Undergoing In Vitro Fertilisation or Intracytoplasmic Sperm Injection Procedures
- Conditions
- First Posted Date
- 2018-01-09
- Last Posted Date
- 2023-02-09
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 1018
- Registration Number
- NCT03393780
- Locations
- 🇮🇹
Policlinico di Milano (there may be other sites in this country), Milan, Italy
🇵🇱Invicta Fertility Clinic Gdansk (there may be other sites in this country), Gdańsk, Poland
🇳🇱Erasmus Medisch Centrum (there may be other sites in this country), Rotterdam, Netherlands
Step Down FSH Approach and Late Follicular Phase in Progesterone Level
- Conditions
- Interventions
- First Posted Date
- 2017-11-29
- Last Posted Date
- 2020-09-09
- Lead Sponsor
- ART Fertility Clinics LLC
- Target Recruit Count
- 127
- Registration Number
- NCT03356964
- Locations
- 🇦🇪
IVI Middle East Fertilty Clinic, Abu Dhabi, United Arab Emirates
Efficacy and Safety of FE 999049 in Controlled Ovarian Stimulation in Pan-Asian Women
- Conditions
- Interventions
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2023-08-24
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 1011
- Registration Number
- NCT03296527
- Locations
- 🇨🇳
Beijing Obstetrics and Gynecology Hospital,Capital Medical University, Beijing, China
🇨🇳ShengJing Hospital of China Medical University, Shenyang, China
🇨🇳The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
Efficacy and Safety of FE 999049 in Controlled Ovarian Stimulation in Japanese Women
- First Posted Date
- 2017-07-25
- Last Posted Date
- 2023-08-24
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 373
- Registration Number
- NCT03228680
- Locations
- 🇯🇵
Investigational Site 8121, Chiba-shi, Chiba, Japan
🇯🇵Yachiyo Hospital, Anjo, Aichi, Japan
🇯🇵Saint Women's Clinic, Saitama, Japan
Optimisation of Follicular Recruitment in IVM Cycles
- First Posted Date
- 2017-06-23
- Last Posted Date
- 2023-04-07
- Lead Sponsor
- Universitair Ziekenhuis Brussel
- Target Recruit Count
- 145
- Registration Number
- NCT03197077
- Locations
- 🇧🇪
UZ Brussel, Brussels, Belgium
Gonapure® in Multifollicular Stimulation in Egyptian Women Undergoing IVF/ICSI
- First Posted Date
- 2017-02-20
- Last Posted Date
- 2017-08-30
- Lead Sponsor
- MinaPharm Pharmaceuticals
- Target Recruit Count
- 200
- Registration Number
- NCT03057574
- Locations
- 🇪🇬
Alexandria University, Alexandria, Egypt
🇪🇬Ain Shams University, Cairo, Egypt
Effectiveness and Safety Study of Fixed Versus Flexible of Gonadotropin-releasing Hormone Antagonist Protocol
- Conditions
- Interventions
- First Posted Date
- 2015-12-21
- Last Posted Date
- 2015-12-21
- Lead Sponsor
- Chong Qing Reproducive and Genetic Institute
- Target Recruit Count
- 200
- Registration Number
- NCT02635607
Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients
- First Posted Date
- 2015-06-09
- Last Posted Date
- 2017-08-22
- Lead Sponsor
- Vietnam National University
- Target Recruit Count
- 400
- Registration Number
- NCT02466204
- Locations
- 🇻🇳
Research Center for Genetics and Reproductive Health, Ho Chi Minh City, Vietnam
🇻🇳My Duc Hospital, Ho Chi Minh City, Vietnam
FSH Receptor Polymorphism p.N680S and Efficacy of FSH Therapy
- First Posted Date
- 2015-01-29
- Last Posted Date
- 2016-07-12
- Lead Sponsor
- Azienda USL Modena
- Target Recruit Count
- 88
- Registration Number
- NCT02349945
- Locations
- 🇩🇪
Zentrums für Reproduktions-medizin und Andrologie Universitätsklinikum Halle (Saale), Martin-Luther-Universität Halle-Wittenberg, Halle, Germany
🇮🇹AziendaUSLModena, Modena, Italy
🇮🇹Department of Medical Pathophysiology, University of Rome La Sapienza, Lab of Seminology & Immunology of Reproduction, Rome, Italy
Drug Development Updates
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