Follitropin
- Generic Name
- Follitropin
- Brand Names
- Bemfola, Follistim, Gonal F, Gonal-F, Menopur, Ovaleap, Pergoveris, Puregon, GONAL-f, Rekovelle
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 146479-72-3
- Unique Ingredient Identifier
- 2M2GGL7HUP
- Background
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glyco...
- Indication
In women having been diagnosed with primary ovarian failure, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility. In men with hypogonadotrophic hypogonadism, it is used to induce spermatogenesis. Follitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use...
- Associated Conditions
- -
- Associated Therapies
- Assisted Reproductive Technology therapy, Controlled Ovarian Stimulation
Efficacy and Tolerability of Human FSH Versus Recombinant FSH (Follitropin Alpha) in ICSI.
- First Posted Date
- 2006-06-12
- Last Posted Date
- 2015-03-27
- Lead Sponsor
- IBSA Institut Biochimique SA
- Target Recruit Count
- 151
- Registration Number
- NCT00335725
- Locations
- 🇭🇺
Semmelweis Medical School, Budapest, Hungary
🇫🇷Hôpital Edouard Herriot, Lyon, France
🇫🇷Institut de Médecine de la Reproduction, Marseille, France
A Study of the Efficacy and Safety of Highly Purified Menotrophin Versus Recombinant Follitropin Alfa
- First Posted Date
- 2005-11-23
- Last Posted Date
- 2010-02-26
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 80
- Registration Number
- NCT00257556
- Locations
- 🇬🇧
The Royal Hallamshire Hospital, University of Sheffield, Jessop Wing, Tree Root Walk, Sheffield, United Kingdom
🇬🇧Leeds General Infirmary, Great George Street, Leeds, United Kingdom
🇩🇪Gemeinschaftspraxis und Tagesklinik, Zingel 29, Hildesheim, Germany
Luteal Phase FSH in the IVF Poor Responder
- First Posted Date
- 2005-09-23
- Last Posted Date
- 2015-12-03
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 20
- Registration Number
- NCT00225433
- Locations
- 🇺🇸
University of Pennsylvania Reproductive Research Unit, Philadelphia, Pennsylvania, United States
Drug Development Updates
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