Caffeine
- Generic Name
- Caffeine
- Brand Names
- Anacin, Arthriten Inflammatory Pain, Ascomp, Bc Arthritis, Bc Original Formula, Cafcit, Diurex, Dvorah, Esgic, Exaprin, Excedrin, Excedrin Tension Headache, Fioricet, Fioricet With Codeine, Fiorinal, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Midol Complete, Midol Cramps & Bodyaches, Migergot, Norgesic, Norgesic Forte, Orbivan, Orphengesic, Pamprin Max Formula, Peyona, Stanback Headache Powder Reformulated Jan 2011, Trezix, Trianal, Trianal C, Triatec, Triatec-8, Vanatol, Vanatol S, Vanquish, Vivarin, Peyona (previously Nymusa), Gencebok
- Drug Type
- Small Molecule
- Chemical Formula
- C8H10N4O2
- CAS Number
- 58-08-2
- Unique Ingredient Identifier
- 3G6A5W338E
- Background
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine. It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, whic...
- Indication
Caffeine is indicated for the short term treatment of apnea of prematurity in infants and off label for the prevention and treatment of bronchopulmonary dysplasia caused by premature birth. In addition, it is indicated in combination with sodium benzoate to treat respiratory depression resulting from an overdose with CNS depressant drugs. Caffeine has a broa...
- Associated Conditions
- Acute Pain, Chronic Lung Disease of Prematurity, Common Cold, Dyspepsia, Fatigue, Fever, Flu caused by Influenza, Headache, Menstrual Pain, Myalgia, Pain, Pain caused by Rheumatism, Primary apnea of premature newborns, Respiratory Depression, Somnolence, Tension Headache, Toothache, Under-eyes Dark Circles, Vascular Headaches, Moderate Pain
- Associated Therapies
- Analgesia, Antacid therapy, Athletic Performance
Caffeine Versus Placebo for Spinal Headaches
- Conditions
- Interventions
- First Posted Date
- 2008-12-17
- Last Posted Date
- 2013-10-29
- Lead Sponsor
- United States Naval Medical Center, Portsmouth
- Target Recruit Count
- 21
- Registration Number
- NCT00809627
- Locations
- 🇺🇸
Emergency Department, Naval Medical Center Portsmouth, Portsmouth, Virginia, United States
Determine the Effect of Multiple Doses of AZD7325, CYP Study
- First Posted Date
- 2008-11-13
- Last Posted Date
- 2008-11-13
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 24
- Registration Number
- NCT00790114
Efficacy of ONE A DAY Weightsmart Advanced Versus Caffeine and Placebo on Energy Expenditure, Thermogenesis and Perceived Energy Levels in Women.
- Conditions
- Interventions
- First Posted Date
- 2008-10-29
- Last Posted Date
- 2018-12-19
- Lead Sponsor
- Bayer
- Target Recruit Count
- 22
- Registration Number
- NCT00781586
The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects and in Patients With Ischemic Heart Disease
- First Posted Date
- 2007-11-28
- Last Posted Date
- 2010-02-25
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 80
- Registration Number
- NCT00564824
- Locations
- 🇮🇱
Heart Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel
Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients
- Conditions
- Interventions
- First Posted Date
- 2007-07-02
- Last Posted Date
- 2012-03-01
- Target Recruit Count
- 85
- Registration Number
- NCT00495092
- Locations
- 🇪🇸
Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain
Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence
- First Posted Date
- 2007-07-02
- Last Posted Date
- 2010-05-27
- Target Recruit Count
- 108
- Registration Number
- NCT00495183
- Locations
- 🇪🇸
Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain
Effects of Low Doses of Caffeine on Mood, Physiology and Mental Function
- First Posted Date
- 2007-06-18
- Last Posted Date
- 2015-10-08
- Lead Sponsor
- Northumbria University
- Target Recruit Count
- 20
- Registration Number
- NCT00487227
Study To Investigate If Repeat Doses Of GSK598809 Are Safe And Well Tolerated And To Evaluate Blood Levels Of GSK598809
- Conditions
- Interventions
- First Posted Date
- 2007-02-21
- Last Posted Date
- 2017-07-31
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 104
- Registration Number
- NCT00437632
- Locations
- 🇬🇧
GSK Investigational Site, London, United Kingdom
Does Caffeine Reduce Dipyridamole-Induced Protection Against Ischemia-Reperfusion Injury?
- Conditions
- Interventions
- First Posted Date
- 2007-02-01
- Last Posted Date
- 2008-07-29
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 20
- Registration Number
- NCT00430170
- Locations
- 🇳🇱
Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
"Pecos" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous Fat
- Conditions
- First Posted Date
- 2006-09-19
- Last Posted Date
- 2016-01-25
- Lead Sponsor
- Pennington Biomedical Research Center
- Target Recruit Count
- 96
- Registration Number
- NCT00377975
- Locations
- 🇺🇸
Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States
Drug Development Updates
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