Caffeine

Generic Name
Caffeine
Brand Names
Anacin, Arthriten Inflammatory Pain, Ascomp, Bc Arthritis, Bc Original Formula, Cafcit, Diurex, Dvorah, Esgic, Exaprin, Excedrin, Excedrin Tension Headache, Fioricet, Fioricet With Codeine, Fiorinal, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Midol Complete, Midol Cramps & Bodyaches, Migergot, Norgesic, Norgesic Forte, Orbivan, Orphengesic, Pamprin Max Formula, Peyona, Stanback Headache Powder Reformulated Jan 2011, Trezix, Trianal, Trianal C, Triatec, Triatec-8, Vanatol, Vanatol S, Vanquish, Vivarin, Peyona (previously Nymusa), Gencebok
Drug Type
Small Molecule
Chemical Formula
C8H10N4O2
CAS Number
58-08-2
Unique Ingredient Identifier
3G6A5W338E
Background

Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine. It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, whic...

Indication

Caffeine is indicated for the short term treatment of apnea of prematurity in infants and off label for the prevention and treatment of bronchopulmonary dysplasia caused by premature birth. In addition, it is indicated in combination with sodium benzoate to treat respiratory depression resulting from an overdose with CNS depressant drugs. Caffeine has a broa...

Associated Conditions
Acute Pain, Chronic Lung Disease of Prematurity, Common Cold, Dyspepsia, Fatigue, Fever, Flu caused by Influenza, Headache, Menstrual Pain, Myalgia, Pain, Pain caused by Rheumatism, Primary apnea of premature newborns, Respiratory Depression, Somnolence, Tension Headache, Toothache, Under-eyes Dark Circles, Vascular Headaches, Moderate Pain
Associated Therapies
Analgesia, Antacid therapy, Athletic Performance
Clinical Trials
Related News

Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea

Not Applicable
Completed
Conditions
Sleep Apnea
Interventions
Drug: Dextromethorphan
Drug: Caffeine
First Posted Date
2006-04-03
Last Posted Date
2009-03-19
Lead Sponsor
Virginia Commonwealth University
Target Recruit Count
69
Registration Number
NCT00310323
Locations
🇺🇸

University of Louisville, Louisville, Kentucky, United States

🇺🇸

Virginia Commonwealth University, Richmond, Virginia, United States

The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA).

First Posted Date
2006-01-09
Last Posted Date
2016-06-16
Lead Sponsor
The University of Texas Health Science Center, Houston
Target Recruit Count
74
Registration Number
NCT00273754
Locations
🇺🇸

University of Texas, Health Science Center at Houston, Children's Memorial Hermann Hospital, Houston, Texas, United States

Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole

Not Applicable
Completed
Conditions
Hyperemia
Hypoxia
First Posted Date
2005-12-22
Last Posted Date
2008-03-28
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
12
Registration Number
NCT00268554
Locations
🇳🇱

Radboud university Nijmegen Medical Centre, Nijmegen, Gelderland, Netherlands

Does Caffeine Affect the Sensitivity of Adenosine Perfusion Scans?

First Posted Date
2005-09-20
Last Posted Date
2012-10-29
Lead Sponsor
University of Wisconsin, Madison
Target Recruit Count
50
Registration Number
NCT00205166
Locations
🇺🇸

University of Wisconsin, Madison, Wisconsin, United States

The Effect of Caffeine on Ischemic Preconditioning

First Posted Date
2005-09-16
Last Posted Date
2006-11-29
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
24
Registration Number
NCT00184912
Locations
🇳🇱

Radboud University Nijmegen Medical Centre / Department of Pharmacology and Toxicology, Nijmegen, Gelderland, Netherlands

Adenosine Receptors Influence Ischemia-Reperfusion Injury

Not Applicable
Suspended
Conditions
Ischemia-Reperfusion Injury
First Posted Date
2005-09-16
Last Posted Date
2008-03-28
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
8
Registration Number
NCT00184847
Locations
🇳🇱

Radboud University Nijmegen Medical Centre/Department of Pharmacology and Toxicology, Nijmegen, Gelderland, Netherlands

Metabolic Capacity of Israeli Populations

First Posted Date
2005-09-13
Last Posted Date
2018-06-12
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
1200
Registration Number
NCT00162383
Locations
🇮🇱

Hadassah Medical Organization, Jerusalem, Israel

Coronary Care Caffeine: Influence of Coffee on Heart Rate Post Myocardial Infarction

Completed
Conditions
Myocardial Infarction
First Posted Date
2005-08-29
Last Posted Date
2009-10-05
Lead Sponsor
The Royal Bournemouth Hospital
Target Recruit Count
100
Registration Number
NCT00137098
Locations
🇬🇧

Royal Bournemouth Hospital, Bournemouth, Dorset, United Kingdom

Caffeine in the Prevention of Post-operative Nausea and Vomiting

Not Applicable
Completed
Conditions
Postoperative Nausea and Vomiting
Interventions
Drug: Caffeine
First Posted Date
2005-08-15
Last Posted Date
2017-02-07
Lead Sponsor
Beth Israel Deaconess Medical Center
Target Recruit Count
135
Registration Number
NCT00130026
Locations
🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

The Effect of Caffeine in Elderly Citizens

Phase 4
Completed
Conditions
Healthy Elderly Citizens
First Posted Date
2005-07-07
Last Posted Date
2006-07-07
Lead Sponsor
Herning Hospital
Target Recruit Count
30
Registration Number
NCT00117520
Locations
🇩🇰

Surgical Research Department, Herning, Ringkjoebing, Denmark

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