Caffeine
- Generic Name
- Caffeine
- Brand Names
- Anacin, Arthriten Inflammatory Pain, Ascomp, Bc Arthritis, Bc Original Formula, Cafcit, Diurex, Dvorah, Esgic, Exaprin, Excedrin, Excedrin Tension Headache, Fioricet, Fioricet With Codeine, Fiorinal, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Midol Complete, Midol Cramps & Bodyaches, Migergot, Norgesic, Norgesic Forte, Orbivan, Orphengesic, Pamprin Max Formula, Peyona, Stanback Headache Powder Reformulated Jan 2011, Trezix, Trianal, Trianal C, Triatec, Triatec-8, Vanatol, Vanatol S, Vanquish, Vivarin, Peyona (previously Nymusa), Gencebok
- Drug Type
- Small Molecule
- Chemical Formula
- C8H10N4O2
- CAS Number
- 58-08-2
- Unique Ingredient Identifier
- 3G6A5W338E
- Background
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine. It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, whic...
- Indication
Caffeine is indicated for the short term treatment of apnea of prematurity in infants and off label for the prevention and treatment of bronchopulmonary dysplasia caused by premature birth. In addition, it is indicated in combination with sodium benzoate to treat respiratory depression resulting from an overdose with CNS depressant drugs. Caffeine has a broa...
- Associated Conditions
- Acute Pain, Chronic Lung Disease of Prematurity, Common Cold, Dyspepsia, Fatigue, Fever, Flu caused by Influenza, Headache, Menstrual Pain, Myalgia, Pain, Pain caused by Rheumatism, Primary apnea of premature newborns, Respiratory Depression, Somnolence, Tension Headache, Toothache, Under-eyes Dark Circles, Vascular Headaches, Moderate Pain
- Associated Therapies
- Analgesia, Antacid therapy, Athletic Performance
A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis
- Conditions
- Interventions
- First Posted Date
- 2023-02-23
- Last Posted Date
- 2024-11-18
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 30
- Registration Number
- NCT05741385
- Locations
- 🇩🇪
CRS Clinical Research Services Mannheim GmbH, Mannheim, Germany
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
- First Posted Date
- 2023-01-17
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- University of Texas at Austin
- Target Recruit Count
- 20
- Registration Number
- NCT05685407
- Locations
- 🇺🇸
The University of Texas at Austin, Sexual Psychophysiology Laboratory, Austin, Texas, United States
Effect of Caffeine Versus Probiotic on Preterm Neonates With Bronchopulmonary Dysplasia
- Conditions
- Interventions
- First Posted Date
- 2023-01-12
- Last Posted Date
- 2023-01-12
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 90
- Registration Number
- NCT05682807
- Locations
- 🇪🇬
Tanta University, Tanta, El Gharbia, Egypt
Drug-Drug Interaction Study Between EDP-235, Midazolam, Caffeine and Rosuvastatin in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2022-10-26
- Last Posted Date
- 2023-04-27
- Lead Sponsor
- Enanta Pharmaceuticals, Inc
- Target Recruit Count
- 24
- Registration Number
- NCT05594615
- Locations
- 🇺🇸
ICON, plc., Salt Lake City, Utah, United States
The Effects of Caffeine on Heart Rate and Heart Rate Variability
- First Posted Date
- 2022-08-30
- Last Posted Date
- 2022-08-30
- Lead Sponsor
- St Mary's University College
- Target Recruit Count
- 16
- Registration Number
- NCT05521386
A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo
- Conditions
- Interventions
- First Posted Date
- 2022-08-03
- Last Posted Date
- 2024-02-08
- Lead Sponsor
- Bayer
- Target Recruit Count
- 541
- Registration Number
- NCT05485805
- Locations
- 🇺🇸
JBR Clinical Research, Salt Lake City, Utah, United States
A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese Participants
- Conditions
- Interventions
- First Posted Date
- 2022-07-06
- Last Posted Date
- 2023-04-18
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 32
- Registration Number
- NCT05445232
- Locations
- 🇺🇸
Covance Dallas, Dallas, Texas, United States
🇺🇸Covance Clinical Research Unit, Daytona Beach, Florida, United States
Influence of Caffeine Consumption on the Human Circadian System
- Conditions
- Interventions
- First Posted Date
- 2022-06-08
- Last Posted Date
- 2022-06-08
- Lead Sponsor
- Psychiatric Hospital of the University of Basel
- Target Recruit Count
- 20
- Registration Number
- NCT05409339
- Locations
- 🇨🇭
UPK Basel, Basel, Basel Stadt, Switzerland
Evaluation of the Potential CYP1A2-mediated Drug Drug Interaction Safety, and Tolerability of ABX464
- First Posted Date
- 2021-11-16
- Last Posted Date
- 2022-01-05
- Lead Sponsor
- Abivax S.A.
- Target Recruit Count
- 59
- Registration Number
- NCT05121714
- Locations
- 🇬🇧
Simbec-Orion, Merthyr Tydfil, United Kingdom
A Study to Estimate the Effect of Multiple Dose Abrocitinib on Caffeine, Efavirenz, and Omeprazole in Healthy Participants
- Conditions
- Interventions
- First Posted Date
- 2021-10-05
- Last Posted Date
- 2024-05-31
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 26
- Registration Number
- NCT05067439
- Locations
- 🇺🇸
Research Centers of America ( Hollywood ), Hollywood, Florida, United States
Drug Development Updates
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