Rolapitant
- Generic Name
- Rolapitant
- Brand Names
- Varubi
- Drug Type
- Small Molecule
- Chemical Formula
- C25H26F6N2O2
- CAS Number
- 552292-08-7
- Unique Ingredient Identifier
- NLE429IZUC
- Background
Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist approved for the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) in adults. Delayed-phase CINV typically occurs >24 hours after chemotherapy treatment and is principally mediated by Neurokinin-1 and its ligand Substance P, which is released in ...
- Indication
This drug is indicated in adults in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy.
- Associated Conditions
- Delayed chemotherapy-induced nausea and vomiting
- Associated Therapies
- -
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