Amlodipine
- Generic Name
- Amlodipine
- Brand Names
- Amlobenz, Azor, Caduet, Dafiro, Exforge, Exforge Hct, Katerzia, Lotrel, Norliqva, Norvasc, Prestalia, Tribenzor, Twynsta, Viacoram
- Drug Type
- Small Molecule
- Chemical Formula
- C20H25ClN2O5
- CAS Number
- 88150-42-9
- Unique Ingredient Identifier
- 1J444QC288
- Background
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnorma...
- Indication
Amlodipine may be used alone or in combination with other antihypertensive and antianginal agents for the treatment of the following conditions :
• Hypertension
• Coronary artery disease
• Chronic stable angina
• Vasospastic angina (Prinzmetal’s or Variant angina)
...
- Associated Conditions
- Cardiovascular Events, Chronic Stable Angina Pectoris, Coronary Artery Disease (CAD), Homozygous Familial Hypercholesterolaemia (HoFH), Hypertension, Hypertension, Essential Hypertension, Mixed Dyslipidemias, Primary Hypercholesterolemia, Vasospastic Angina
- Associated Therapies
- -
MR Antagonist and LSD1
- Conditions
- Interventions
- First Posted Date
- 2021-04-12
- Last Posted Date
- 2024-08-09
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 300
- Registration Number
- NCT04840342
- Locations
- 🇺🇸
Brigham and Women's, Boston, Massachusetts, United States
Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension
- First Posted Date
- 2021-03-10
- Last Posted Date
- 2024-10-28
- Lead Sponsor
- Prisma Health-Upstate
- Target Recruit Count
- 175
- Registration Number
- NCT04790279
- Locations
- 🇺🇸
Greenville Memorial Hospital, Greenville, South Carolina, United States
Anti Inflammatory Treatment of Hypertension
- First Posted Date
- 2021-02-05
- Last Posted Date
- 2021-02-05
- Target Recruit Count
- 200
- Registration Number
- NCT04740840
Treatment of Early Hypertension Among Persons Living With HIV in Haiti
- First Posted Date
- 2020-12-31
- Last Posted Date
- 2024-04-09
- Lead Sponsor
- Weill Medical College of Cornell University
- Target Recruit Count
- 250
- Registration Number
- NCT04692467
- Locations
- 🇭🇹
GHESKIO, Port-au-Prince, Haiti
Personalised Electronic Record Supported Optimisation When Alone for Patients With Hypertension
- First Posted Date
- 2020-09-22
- Last Posted Date
- 2024-02-13
- Lead Sponsor
- Queen Mary University of London
- Target Recruit Count
- 343
- Registration Number
- NCT04559074
- Locations
- 🇬🇧
William Harvey Research Institute Clinical Research Centre, Queen Mary University of London, London, London - City Of London, United Kingdom
🇬🇧Queen Mary University London, London, United Kingdom
Comparing Safety and Efficacy of Amlodipine Verses S Amlodipine in Patients With Essential Hypertension
- Conditions
- Interventions
- First Posted Date
- 2020-09-18
- Last Posted Date
- 2020-11-12
- Lead Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
- Target Recruit Count
- 80
- Registration Number
- NCT04554303
- Locations
- 🇰🇷
Korea University Guro Hospital, Seoul, Korea, Republic of
Management of Hypertension Utilizing Trained Community Health Worker in Rural Municipalities of Nepal
- Conditions
- Interventions
- First Posted Date
- 2020-08-20
- Last Posted Date
- 2022-07-29
- Lead Sponsor
- Johns Hopkins Bloomberg School of Public Health
- Target Recruit Count
- 1428
- Registration Number
- NCT04521582
- Locations
- 🇳🇵
Rupa Rural Municipality, Kaski, Gandaki, Nepal
🇳🇵Biruwa Rural Municipality, Syangja, Gandaki, Nepal
Sympathoinhibition as a Preferred Second Line Treatment of Obesity Related Hypertension
- Conditions
- Interventions
- First Posted Date
- 2020-07-17
- Last Posted Date
- 2022-09-29
- Lead Sponsor
- Royal Perth Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT04474899
- Locations
- 🇦🇺
Dobney Hypertension Centre, Perth, Western Australia, Australia
BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF
- Conditions
- Interventions
- First Posted Date
- 2020-06-17
- Last Posted Date
- 2024-07-09
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 50
- Registration Number
- NCT04434664
- Locations
- 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Bioequivalence of Levamlodipine Besylate Tablets in Healthy Chinese Subjects
- Conditions
- Interventions
- First Posted Date
- 2020-06-02
- Last Posted Date
- 2020-06-05
- Lead Sponsor
- The Affiliated Hospital of Qingdao University
- Target Recruit Count
- 48
- Registration Number
- NCT04411875
- Locations
- 🇨🇳
Phase Ⅰ Clinical Research Center, Qingdao, Shandong, China
Drug Development Updates
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