Overview
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Indication
Antipyrine is an analgesic often used to test effects of other drugs on liver enzymes. In combination with benzocaine in otic solutions, antipyrine is indicated for the symptomatic relief of acute otitis media arising from various etiologies.
Associated Conditions
- Cough
- Otitis Media (OM)
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2014/01/16 | Phase 2 | Completed | Currax Pharmaceuticals |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Rebel Distributors Corp | 21695-216 | AURICULAR (OTIC) | 54 mg in 1 mL | 12/2/2009 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| TROPEX EAR DROPS 5% w/v | SIN04739P | SOLUTION | 5% w/v | 6/26/1990 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| NEW-PAIN-Q CAP | N/A | N/A | N/A | 6/20/1990 | |
| TROPEX EAR DROPS 5% | N/A | N/A | N/A | 2/11/1998 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| EARCLEAR EAR ACHE RELIEF ear drops bottle | 125789 | Medicine | A | 2/27/2006 | |
| AURALGAN EAR DROPS | 10460 | Medicine | A | 7/4/1991 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| AURALGAN | paladin pharma inc. | 02332477 | Solution - Otic | 54 MG / ML | 2/28/2011 |
| ARTROL | les produits gerbex inc. | 00109908 | Liquid - Oral | 142 MG / 30 ML | 12/31/1968 |
| AURALGAN SOLUTION | wyeth consumer healthcare inc. | 01932403 | Solution - Otic | 54 MG / ML | 12/31/1993 |
| AURALGAN EARDROPS | wyeth canada | 02041502 | Drops - Otic | 54 MG / ML | 12/31/1994 |
| OTI CAL | produits francais labs inc. | 00540943 | Drops - Otic | 58 MG / ML | 12/31/1981 |
| HOMEOPATHIC MEDICINE (S NO. 313) DPS 30C | total health centre | 02077329 | Drops - Oral | 30 C / ML | 12/31/1994 |
| ANTIDOULEURS REZALL | produits francais labs inc. | 00363855 | Liquid - Oral | 180 MG / 30 ML | 12/31/1930 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| Epistaxol solución cutánea | Medical S.A. | 42972 | SOLUCIÓN CUTÁNEA | Sin Receta | Commercialized |
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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