Prucalopride
- Generic Name
- Prucalopride
- Brand Names
- Motegrity, Resolor, Resotran
- Drug Type
- Small Molecule
- Chemical Formula
- C18H26ClN3O3
- CAS Number
- 179474-81-8
- Unique Ingredient Identifier
- 0A09IUW5TP
- Background
Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride...
- Indication
Prucalopride is indicated for the treatment of chronic idiopathic constipation (CIC) in adults.
CIC is one of the most common chronic functional gastrointestinal disorders worldwide. The diagnosis of this agent is very hard and it can be confirmed if the patient experience at least two of the following:
...
- Associated Conditions
- Opioid Induced Constipation (OIC), Chronic idiopathic constipation (CIC), Refractory Chronic idiopathic constipation
- Associated Therapies
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