Pantoprazole

Generic Name: Pantoprazole

Brand Names: Protonix, Somac Control, Tecta, Pantozol Control, Controloc Control

Drug Type: Small Molecule

Chemical Formula: C_₁₆H_₁₅F_₂N_₃O_₄S

CAS Number: 102625-70-7

Unique Ingredient Identifier: D8TST4O562

Background: Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...

Indication: Pantoprazole Injection:

Treatment of gastroesophageal reflux disease associated with a history of erosive esophagitis
...

Associated Conditions: Erosive Esophagitis, GERD With Erosive Esophagitis, Gastro-esophageal Reflux Disease (GERD), Healing, Heartburn, Helicobacter Pylori Infection, Stress Ulcers, Zollinger-Ellison Syndrome, Conditions where a reduction of gastric acid secretion is required, Pathological hypersecretory conditions

Associated Therapies: -

Clinical Trials

Bioavailability of Oral BIRB 796 BS Tablets With and Without Administration of Oral Pantoprazole in Healthy Male Volunteers

Phase 1

Completed

Conditions: Healthy

Interventions: Device: BIBR 796 BS
Drug: Pantoprazole

First Posted Date: 2014-08-06

Last Posted Date: 2014-08-06

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 22

Registration Number: NCT02209831

PK Study With Pantoprazole in Obese Children and Adolescents

Phase 1

Completed

Conditions: Gastroesophageal Reflux Disease

Interventions: Drug: Pantoprazole

First Posted Date: 2014-07-10

Last Posted Date: 2019-09-17

Lead Sponsor: Phillip Brian Smith

Target Recruit Count: 41

Registration Number: NCT02186652

Locations: 🇺🇸
University of Arkansas, Little Rock, Arkansas, United States
🇺🇸
Children's Mercy Hospital, Kansas City, Missouri, United States
🇺🇸
East Carolina University, Greenville, North Carolina, United States

and more 1 locations

BIBR 953 ZW in Healthy Elderly Subjects

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: BIBR 1048 MS
Drug: Pantoprazole

First Posted Date: 2014-06-25

Last Posted Date: 2014-06-25

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 36

Registration Number: NCT02173730

Bioavailability of BIBR 963 ZW After 50 mg of BIBR 1048 MS With and Without of Pantoprazole in Healthy Subjects

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: BIBR 1048 MS Capsule D
Drug: BIBR 1048 MS tartaric acid solution
Drug: BIBR 1048 MS Capsule C
Drug: BIBR 1048 MS Capsule A
Drug: BIBR 1048 MS Capsule B
Drug: Pantoprazole

First Posted Date: 2014-06-23

Last Posted Date: 2014-06-23

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 16

Registration Number: NCT02170896

Bioavailability of BIBR 953 ZW in Healthy Subjects

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: BIBR 1048 low1
Drug: BIBR 1048 low2
Drug: BIBR 1048 medium
Drug: BIBR 1048 high
Drug: Pantoprazole

First Posted Date: 2014-06-23

Last Posted Date: 2014-06-23

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 48

Registration Number: NCT02170766

Bioavailability of BIBR 1048 MS With and Without Pantoprazole Under Influence of Food in Healthy Subjects

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: BIBR 1048 MS
Drug: Pantoprazole

First Posted Date: 2014-06-23

Last Posted Date: 2014-06-23

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 18

Registration Number: NCT02170610

Bioavailability of BIBR 953 ZW After Oral Administration of BIBR 1048 MS in Healthy Subjects

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: BIBR 1048 MS Capsule E
Drug: BIBR 1048 MS Capsule F
Drug: BIBR 1048 MS Capsule G
Drug: BIBR 1048 MS Tablet H
Drug: BIBR 1048 MS Drinking solution
Drug: Pantoprazole

First Posted Date: 2014-06-23

Last Posted Date: 2014-06-23

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 15

Registration Number: NCT02170636

Bioavailability of BIBR 953 ZW After Administration of BIBR 1048 MS in Healthy Subjects

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: BIBR 1048 MS Capsule I
Drug: BIBR 1048 MS Capsule K
Drug: Pantoprazole
Drug: BIBR 1048 MS drinking solution

First Posted Date: 2014-06-23

Last Posted Date: 2014-06-23

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 12

Registration Number: NCT02170623

Bioavailability of BIBR 1048 MS Single Doses With or Without Pantoprazole in Healthy Subjects

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: BIBR 1048 MS capsule formulation A
Drug: BIBR 1048 MS capsule formulation B
Drug: BIBR 1048 MS powder plus solution
Drug: Pantoprazole

First Posted Date: 2014-06-23

Last Posted Date: 2014-06-23

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 24

Registration Number: NCT02170805

Stereotactic Radiosurgery in Metastatic Spinal Cord Compression

Not Applicable

Terminated

Conditions: Spinal Cord Compression
Neoplasm Metastasis

Interventions: Procedure: Decompression surgery
Radiation: Radiosurgery
Radiation: Fractionated Radiotherapy
Drug: Glucocorticoids
Drug: Pantoprazole

First Posted Date: 2014-06-19

Last Posted Date: 2021-03-11

Lead Sponsor: Rigshospitalet, Denmark

Target Recruit Count: 10

Registration Number: NCT02167633

Locations: 🇩🇰
Rigshospitalet, Copenhagen, Denmark

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