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Tilarginine

Generic Name
Tilarginine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C7H16N4O2
CAS Number
17035-90-4
Unique Ingredient Identifier
27JT06E6GR
Background

Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow.

Associated Conditions
-
Associated Therapies
-
nature.com
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NOS inhibition sensitizes metaplastic breast cancer to PI3K inhibition and taxane therapy

L-NMMA combined with taxane shows clinical activity in MpBC patients, targeting NOS signaling. The combination therapy resulted in a 46% clinical benefit rate and 23% overall response rate, with manageable toxicity. NOS inhibition, alongside PI3K inhibition, enhances tumor response and reverses EMT in MpBC, suggesting a promising therapeutic strategy.
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