Cilostazol

Generic Name
Cilostazol
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C20H27N5O2
CAS Number
73963-72-1
Unique Ingredient Identifier
N7Z035406B
Background

Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reduci...

Indication

Indicated for the alleviation of symptoms of intermittent claudication (pain in the legs that occurs with walking and disappears with rest).

Associated Conditions
Intermittent Claudication
Associated Therapies
-

Cilostazol Stroke Prevention Study : A Placebo-controlled Double-blind Trial for Secondary Prevention of Cerebral Infarction.

First Posted Date
2008-10-06
Last Posted Date
2021-03-01
Lead Sponsor
Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
1095
Registration Number
NCT00766545

Effect of Cilostazol in the Acute Lacunar Infarction Based on Pulsatility Index of Transcranial Doppler

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-08-26
Last Posted Date
2011-09-05
Lead Sponsor
Inje University
Target Recruit Count
203
Registration Number
NCT00741286
Locations
🇰🇷

Wonju Christian Hospital, Wonju, Korea, Republic of

🇰🇷

Sanbon Medical Center, Gunpo, Korea, Republic of

🇰🇷

Ajou University Hospital, Suwon, Korea, Republic of

and more 5 locations

Bioequivalency Study of 100 mg Cilostazol Tablets Under Fasting Conditions

Not Applicable
Completed
Conditions
First Posted Date
2008-01-28
Last Posted Date
2018-01-23
Lead Sponsor
Roxane Laboratories
Target Recruit Count
32
Registration Number
NCT00602173
Locations
🇺🇸

CEDRA Clinical Research, LLC, Austin, Texas, United States

Bioequivalency Study of 50 mg Cilostazol Tablets Under Fasting Conditions

Not Applicable
Completed
Conditions
First Posted Date
2008-01-28
Last Posted Date
2018-01-23
Lead Sponsor
Roxane Laboratories
Target Recruit Count
36
Registration Number
NCT00602407
Locations
🇺🇸

CEDRA Clinical Research, LLC, Austin, Texas, United States

Triple Versus Dual Antiplatelet Therapy After ABT578-Eluting Stent

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-01-10
Last Posted Date
2010-03-18
Lead Sponsor
CardioVascular Research Foundation, Korea
Target Recruit Count
486
Registration Number
NCT00589927
Locations
🇰🇷

Seoul Veterans Hospital, Seoul, Korea, Republic of

🇰🇷

Ulsan University Hospital, Ulsan, Korea, Republic of

🇰🇷

Asan Medical Center, Seoul, Korea, Republic of

and more 7 locations

Effects of Cilostazol on Plasma Adipocytokine and Arterial Stiffness

First Posted Date
2007-12-14
Last Posted Date
2007-12-14
Lead Sponsor
Korea University Anam Hospital
Target Recruit Count
48
Registration Number
NCT00573950
Locations
🇰🇷

Korea Univerisity Anam Hospital, Seoul, Korea, Republic of

Safety and Pharmacokinetics of Probucol and Cilostazol

Phase 4
Completed
Conditions
Interventions
First Posted Date
2007-10-26
Last Posted Date
2022-03-04
Lead Sponsor
Korea Otsuka Pharmaceutical Co., Ltd.
Target Recruit Count
32
Registration Number
NCT00549978
Locations
🇰🇷

Clinical Trial Center, Seoul National University Hospital, Seoul, Korea, Republic of

Overcome Biochemical Aspirin Resistance Through Cilostazol Combination

Phase 4
Completed
Conditions
Interventions
First Posted Date
2007-03-13
Last Posted Date
2010-01-18
Lead Sponsor
Asan Medical Center
Target Recruit Count
244
Registration Number
NCT00446641
Locations
🇰🇷

Jae-Kwan Cha, Busan, Korea, Republic of

🇰🇷

Kangdong Sacred Heart Hospital, Hallym University, Seoul, Korea, Republic of

🇰🇷

Eulji University Hospital, Daejon, Korea, Republic of

and more 1 locations

Efficacy and Safety of HMR1766 in Patients With Fontaine Stage II Peripheral Arterial Disease

First Posted Date
2007-03-05
Last Posted Date
2018-05-17
Lead Sponsor
Sanofi
Target Recruit Count
553
Registration Number
NCT00443287
Locations
🇿🇦

Sanofi-Aventis Administrative Office, Midrand, South Africa

Effects of Cilostazol on VEGF and Oxidative Stress Biomarkers in Hemodialysis Patients With Peripheral Vascular Disease

First Posted Date
2007-02-05
Last Posted Date
2015-05-12
Lead Sponsor
Tungs' Taichung Metroharbour Hospital
Target Recruit Count
40
Registration Number
NCT00431249
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