MedPath

Vincristine

Generic Name
Vincristine
Brand Names
Marqibo, Vincasar
Drug Type
Small Molecule
Chemical Formula
C46H56N4O10
CAS Number
57-22-7
Unique Ingredient Identifier
5J49Q6B70F

Overview

Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate is often chosen as part of polychemotherapy because of lack of significant bone–marrow suppression (at recommended doses) and of unique clinical toxicity (neuropathy).

Background

Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate is often chosen as part of polychemotherapy because of lack of significant bone–marrow suppression (at recommended doses) and of unique clinical toxicity (neuropathy).

Indication

Treatment of acute lymphocytic leukemia (ALL), Hodgkin lymphoma, non-Hodgkin lymphomas, Wilms' tumor, neuroblastoma, rhabdomyosarcoma. Liposomal vincristine is indicated for the treatment of relapsed Philadelphia chromosome-negative (Ph-) acute lymphoblastic leukemia (ALL).

Associated Conditions

  • Acute Lymphoblastic Leukemia (ALL)
  • Choriocarcinoma
  • Chronic Lymphocytic Leukemia
  • Ewing's Sarcoma
  • Gestational Trophoblastic Neoplasia
  • Hepatoblastomas
  • Hodgkin's Lymphoma
  • Immune Thrombocytopenia (ITP)
  • Kaposi's Sarcoma
  • Multiple Myeloma (MM)
  • Neuroblastoma (NB)
  • Non-Hodgkin's Lymphoma (NHL)
  • Ovarian germ cell tumour
  • Pheochromocytoma
  • Relapsed Acute Lymphoblastic Leukemia (ALL)
  • Retinoblastoma
  • Rhabdomyosarcomas
  • Small Cell Lung Cancer (SCLC)
  • Wilms' tumor
  • Advanced Thymoma

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath