Phenylpropanolamine
- Generic Name
- Phenylpropanolamine
- Drug Type
- Small Molecule
- Chemical Formula
- C9H13NO
- CAS Number
- 14838-15-4
- Unique Ingredient Identifier
- 33RU150WUN
- Background
Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
- Indication
For the treatment of nasal congestion, control of urinary incontinence, priapism and obesity.
- Associated Conditions
- Allergy-Induced Respiratory Symptoms, Bronchitis, Common Cold, Cough, Nasal Congestion, Rhinorrhoea, Excess mucus or phlegm
Phase 1/2 Study of CG200745 PPA for Myelodysplastic Syndrome
- First Posted Date
- 2016-04-14
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- CrystalGenomics, Inc.
- Target Recruit Count
- 36
- Registration Number
- NCT02737462
- Locations
- 🇰🇷
Asan Medical Center, Samsung Medical Center, Seoul National University Hospital, Seoul, Korea, Republic of
Study of CG200745 PPA in Combination With Gemcitabine and Erlotinib for Advanced Pancreatic Cancer
Phase 1
- Conditions
- Pancreatic Neoplasms
- Interventions
- First Posted Date
- 2016-04-13
- Last Posted Date
- 2019-06-17
- Lead Sponsor
- CrystalGenomics, Inc.
- Target Recruit Count
- 24
- Registration Number
- NCT02737228
- Locations
- 🇰🇷
Yonsei University Health System, Seoul, Korea, Republic of
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