Overview
Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Indication
For the treatment of nasal congestion, control of urinary incontinence, priapism and obesity.
Associated Conditions
- Allergy-Induced Respiratory Symptoms
- Bronchitis
- Common Cold
- Cough
- Nasal Congestion
- Rhinorrhoea
- Excess mucus or phlegm
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2016/04/14 | Phase 1 | Active, not recruiting | CrystalGenomics, Inc. | ||
2016/04/13 | Phase 1 | UNKNOWN | CrystalGenomics, Inc. |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Pegasus Laboratories, Inc. | 49427-921 | ORAL | 50 1 in 1 1 | 4/21/2025 | |
| Pegasus Laboratories, Inc. | 49427-920 | ORAL | 25 1 in 1 1 | 4/18/2025 | |
| Pegasus Laboratories, Inc. | 49427-922 | ORAL | 75 1 in 1 1 | 4/21/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| JEM C P P TAB | N/A | N/A | N/A | 8/1/1979 | |
| UNI-VASIN LIQUID | N/A | N/A | N/A | 6/14/1979 | |
| D.P.P SYRUP | N/A | N/A | N/A | 7/25/1984 | |
| C.P.P. SYRUP | N/A | N/A | N/A | 7/28/1997 | |
| NEO B P P TAB | N/A | N/A | N/A | 4/12/1984 | |
| BPP SYRUP | N/A | N/A | N/A | 4/27/1979 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| No TGA approvals found for this drug. | |||||
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| DIMETAPP COUGH & COLD LIQUI-GELS - CAP | whitehall-robins inc. | 02215314 | Capsule - Oral | 25 MG | 10/22/1996 |
| ORADRINE-2 TAB | pharmetics (2011) inc | 00763519 | Tablet - Oral | 25 MG | 12/31/1989 |
| CALDOMINE DH ADULTE | technilab pharma inc. | 00550485 | Liquid - Oral | 25 MG / 5 ML | 12/31/1981 |
| DECONGESTANT ANTIHISTAMINIC SYRUP | 00576689 | Elixir - Oral | 5 MG / 5 ML | 12/31/1984 | |
| ORNADE AF LIQUID | smithkline beecham pharma division of smithkline beecham inc | 01918125 | Liquid - Oral | 15 MG / 5 ML | 12/31/1993 |
| SINE-OFF N.D. TAB | smithkline consumer products | 00755990 | Tablet - Oral | 18.75 MG / TAB | 12/31/1988 |
| EMERCIDIN D TAB | pharmetics (2011) inc | 00763519 | Tablet - Oral | 25 MG | 12/31/1989 |
| TRISULFAMINIC TAB | shepherd pharmaceuticals inc. | 00889210 | Tablet - Oral | 12.5 MG | 12/31/1959 |
| TRIAMINIC TIME RELEASE TAB | novartis consumer health canada inc. | 01906593 | Tablet (Extended-Release) - Oral | 50 MG | 12/31/1992 |
| TRIAMINIC EXPECTORANT DH SYRUP | novartis consumer health canada inc. | 01906615 | Syrup - Oral | 12.5 MG / 5 ML | 12/31/1993 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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