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Ambroxol

Generic Name
Ambroxol
Drug Type
Small Molecule
Chemical Formula
C13H18Br2N2O
CAS Number
18683-91-5
Unique Ingredient Identifier
200168S0CL

Overview

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.

Background

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.

Indication

Ambroxol is indicated for secretolytic therapy in bronchoplmonary disease with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing.

Associated Conditions

No associated conditions information available.

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

MUCOCLEAR SYRUP 30 mg/5 ml
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:SYRUP
Strength:30 mg/5 ml
Online:Yes
Approved: 1998/12/12
Approval:SIN10547P
MUCOCLEAR TABLET 30 mg
Manufacturer:SUNWARD PHARMACEUTICAL PRIVATE LIMITED
Form:TABLET
Strength:30 mg
Online:Yes
Approved: 1998/12/12
Approval:SIN10548P
SHINOXOL TABLETS 30 mg
Manufacturer:Y S P INDUSTRIES (M) SDN BHD
Form:TABLET
Strength:30 mg
Online:Yes
Approved: 1992/10/09
Approval:SIN07180P
Mucosolvan 24 Hours Capsule 75mg
Manufacturer:Sanofi Winthrop Industrie
Form:CAPSULE, DELAYED RELEASE
Strength:75mg
Online:Yes
Approved: 2007/11/15
Approval:SIN13373P
POLIBROXOL TABLET 30 mg
Manufacturer:POLIPHARM CO LTD
Form:TABLET
Strength:30 mg
Online:Yes
Approved: 1997/04/16
Approval:SIN09305P

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