MedPath

Ambroxol

Generic Name
Ambroxol
Drug Type
Small Molecule
Chemical Formula
C13H18Br2N2O
CAS Number
18683-91-5
Unique Ingredient Identifier
200168S0CL

Overview

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.

Background

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important role in the body’s natural defence mechanisms. It stimulates synthesis and release of surfactant by type II pneumocytes. Surfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents.

Indication

Ambroxol is indicated for secretolytic therapy in bronchoplmonary disease with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing.

Associated Conditions

No associated conditions information available.

Clinical Trials

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

MUCOSOLVAN LIQUID 30 mg/5 ml
Manufacturer:Delpharm Reims
Form:ELIXIR
Strength:30mg/5ml
Online:Yes
Approved: 1989/06/30
Approval:SIN03515P
AMXOL TABLETS 30 mg
Manufacturer:BIOLAB CO LTD
Form:TABLET
Strength:30 mg
Online:Yes
Approved: 1989/05/20
Approval:SIN02983P
STREPSILS CHESTY COUGH LOZENGE
Manufacturer:RECKITT BENCKISER HEALTHCARE MANUFACTURING (THAILAND) LTD
Form:LOZENGE
Strength:15 mg
Online:Yes
Approved: 2001/11/15
Approval:SIN11716P
AXOL LIQUID 3 mg/ml
Manufacturer:Y S P INDUSTRIES (M) SDN BHD
Form:SOLUTION
Strength:3 mg/ml
Online:Yes
Approved: 1996/11/07
Approval:SIN08999P
MUCOSOLVAN TABLET 30 mg
Manufacturer:Delpharm Reims
Form:TABLET
Strength:30 mg
Online:Yes
Approved: 1989/05/02
Approval:SIN02696P

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