Bupivacaine
- Generic Name
- Bupivacaine
- Brand Names
- Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C18H28N2O
- CAS Number
- 38396-39-3
- Unique Ingredient Identifier
- Y8335394RO
- Background
Bupivacaine is a widely used local anesthetic agent.
- Indication
As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
...
- Associated Conditions
- Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
- Associated Therapies
- General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE
Phase 4
Completed
- Conditions
- Interventions
- First Posted Date
- 2023-10-31
- Last Posted Date
- 2023-10-31
- Lead Sponsor
- Heron Therapeutics
- Target Recruit Count
- 30
- Registration Number
- NCT06109428
- Locations
- 🇺🇸
Endeavor Clinical Trials, LLC, San Antonio, Texas, United States
🇺🇸First Surgical Hospital, Bellaire, Texas, United States
Utility of Exparel Based ESP Blocks in Elective Posterior Spine Fusion
Phase 4
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2023-10-30
- Last Posted Date
- 2023-10-30
- Lead Sponsor
- Hartford Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT06107660
Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block vs Laparoscopic Intraperitoneal Instillation of Local Anesthetic in Pediatrics
Not Applicable
Completed
- Conditions
- Interventions
- First Posted Date
- 2023-10-24
- Last Posted Date
- 2024-04-25
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 66
- Registration Number
- NCT06098105
- Locations
- 🇪🇬
Tanta University, Tanta, El-Gharbia, Egypt
Bilateral Recto-Intercostal Fascial Plane Block in Epigastric Hernia Repair
Not Applicable
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2023-10-23
- Last Posted Date
- 2024-07-23
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 40
- Registration Number
- NCT06092073
- Locations
- 🇪🇬
Tanta University, Tanta, El-Gharbia, Egypt
"Analgesic Efficacy of Combined Transversus Abdominis Plane Block and Posterior Rectus Sheath Block in Patients Undergoing Laparoscopic Appendectomy"
- First Posted Date
- 2023-10-18
- Last Posted Date
- 2023-10-18
- Lead Sponsor
- King Saud Medical City
- Target Recruit Count
- 100
- Registration Number
- NCT06088082
- Locations
- 🇸🇦
Rashid Saeed Khokhar, Riyadh, Saudi Arabia
Comparison of the Effects of Dexamethasone and magnesıum Sulphate Used as Adjuvant in Infraclavicular Nerve Block.
Not Applicable
Completed
- Conditions
- Interventions
- First Posted Date
- 2023-10-17
- Last Posted Date
- 2023-10-17
- Lead Sponsor
- Yuzuncu Yıl University
- Target Recruit Count
- 90
- Registration Number
- NCT06085417
- Locations
- 🇹🇷
Haci Yusuf GUNES, VAN, Turkey
Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain
Phase 2
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2023-10-11
- Last Posted Date
- 2024-01-26
- Lead Sponsor
- Rutgers, The State University of New Jersey
- Target Recruit Count
- 120
- Registration Number
- NCT06077422
- Locations
- 🇺🇸
Rutgers RWJMS, New Brunswick, New Jersey, United States
Regional Anaesthesia
Not Applicable
Completed
- Conditions
- Interventions
- First Posted Date
- 2023-09-26
- Last Posted Date
- 2023-09-26
- Lead Sponsor
- Reham Ali Abdelhaleem Abdelrahman
- Target Recruit Count
- 54
- Registration Number
- NCT06055101
- Locations
- 🇪🇬
Reham Ali Abdelrahman, Cairo, Egypt
Efficacy and Safety of Dexmedetomidine to Bupivacaine in Supraclavicular Brachial Plexus Block
Not Applicable
Completed
- Conditions
- Interventions
- First Posted Date
- 2023-09-01
- Last Posted Date
- 2024-04-02
- Lead Sponsor
- Kafrelsheikh University
- Target Recruit Count
- 75
- Registration Number
- NCT06020781
- Locations
- 🇪🇬
Kafrelsheikh University, Kafr Ash Shaykh, Kafrelsheikh, Egypt
Inter-semispinal Plane Block and Cervical Spine Surgery
Not Applicable
Completed
- Conditions
- Interventions
- First Posted Date
- 2023-08-22
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- Yasser S Mostafa, MD
- Target Recruit Count
- 50
- Registration Number
- NCT06003933
- Locations
- 🇪🇬
Fayoum University Hospital, Fayoum, Faiyum, Egypt
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