Bupivacaine

Generic Name
Bupivacaine
Brand Names
Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
Drug Type
Small Molecule
Chemical Formula
C18H28N2O
CAS Number
38396-39-3
Unique Ingredient Identifier
Y8335394RO
Background

Bupivacaine is a widely used local anesthetic agent.

Indication

As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
...

Associated Conditions
Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
Associated Therapies
General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy

Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study

First Posted Date
2023-08-22
Last Posted Date
2024-11-18
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
45
Registration Number
NCT06004882
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Mid-transverse Process to Pleura Block in Pediatric Thoracotomy

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-08-21
Last Posted Date
2024-01-11
Lead Sponsor
Tanta University
Target Recruit Count
50
Registration Number
NCT05999734

Superficial Cervical Plexus Block and Quality of Recovery After Thyroidectomy

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-08-21
Last Posted Date
2024-10-24
Lead Sponsor
Yale University
Target Recruit Count
160
Registration Number
NCT06002152
Locations
🇺🇸

Yale School of Medicine, New Haven, Connecticut, United States

The PAIN (Pelvic Area Injection for Numbness) Study

First Posted Date
2023-08-02
Last Posted Date
2024-12-09
Lead Sponsor
Montefiore Medical Center
Target Recruit Count
100
Registration Number
NCT05972681
Locations
🇺🇸

Montefiore Medical Center, Bronx, New York, United States

Comparison of Local Anesthetic Dose in Ipack Block Performed in Knee Arthroplasty Operations

First Posted Date
2023-07-27
Last Posted Date
2024-02-13
Lead Sponsor
Istanbul University
Target Recruit Count
112
Registration Number
NCT05963139
Locations
🇹🇷

Istanbul University Istanbul Medical Faculty, Istanbul, Turkey

Comparison Between Bupivacaine and Bupivacaine- Dexamethasone QLB for Postoperative Analgesia

Phase 1
Completed
Conditions
Interventions
First Posted Date
2023-06-26
Last Posted Date
2023-08-24
Lead Sponsor
Ain Shams University
Target Recruit Count
60
Registration Number
NCT05918796
Locations
🇪🇬

Ain Shams University Hospital, Cairo, EL Abassia, Egypt

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

First Posted Date
2023-06-12
Last Posted Date
2023-09-13
Lead Sponsor
Johnny K. Lee
Target Recruit Count
120
Registration Number
NCT05900427
Locations
🇺🇸

NorthShore University HealthSystem, Skokie, Illinois, United States

A Study of Liposomal Bupivacaine Versus 0.25% Bupivacaine Hydrochloride Post Breast Reduction

First Posted Date
2023-06-07
Last Posted Date
2024-04-17
Lead Sponsor
Mayo Clinic
Target Recruit Count
42
Registration Number
NCT05891613
Locations
🇺🇸

Mayo Clinic Minnesota, Rochester, Minnesota, United States

Comparing the Hemodynamic Effects of Epinephrine Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Anaesthesia Assessed by Cardiometry

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-05-16
Last Posted Date
2023-05-16
Lead Sponsor
Kasr El Aini Hospital
Target Recruit Count
39
Registration Number
NCT05860010
Locations
🇪🇬

Kasr Al Ainy, Cairo, Egypt

🇪🇬

Ayman Abougabal [aabougabal], Cairo, Egypt

Efficacy of Dexmedetomidine VS Magnesium Sulphate With Bupivacaine in Erector Spinae Block for Thoracotomy Pain

First Posted Date
2023-05-10
Last Posted Date
2024-02-20
Lead Sponsor
National Cancer Institute, Egypt
Target Recruit Count
60
Registration Number
NCT05851768
Locations
🇪🇬

Walaa Y Elsabeeny, Cairo, Egypt

© Copyright 2024. All Rights Reserved by MedPath