Bupivacaine
- Generic Name
- Bupivacaine
- Brand Names
- Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C18H28N2O
- CAS Number
- 38396-39-3
- Unique Ingredient Identifier
- Y8335394RO
- Background
Bupivacaine is a widely used local anesthetic agent.
- Indication
As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
...
- Associated Conditions
- Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
- Associated Therapies
- General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
US-Guided Serratus Anterior Plane Block Versus Thoracic Epidural in Patients Undergoing Thoracotomy
Not Applicable
Completed
- Conditions
- Interventions
- First Posted Date
- 2023-01-05
- Last Posted Date
- 2023-01-05
- Lead Sponsor
- National Cancer Institute, Egypt
- Target Recruit Count
- 74
- Registration Number
- NCT05672394
- Locations
- 🇪🇬
National Cancer Institute, Cairo, Egypt
ESP Block for Post Cesarean Analgesia
Phase 4
Completed
- Conditions
- Interventions
- First Posted Date
- 2022-12-27
- Last Posted Date
- 2024-01-23
- Lead Sponsor
- Duke University
- Target Recruit Count
- 150
- Registration Number
- NCT05664958
- Locations
- 🇺🇸
Duke University Hospital, Durham, North Carolina, United States
Trial of Liposomal Bupivacaine for TKA
Phase 4
Completed
- Conditions
- Interventions
- First Posted Date
- 2022-12-02
- Last Posted Date
- 2023-07-07
- Lead Sponsor
- Northern Light Mercy Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT05635916
- Locations
- 🇺🇸
Northern Light Mercy Hospital, Portland, Maine, United States
Dexmedetomidine Versus Magnesium Sulphate Added to Bupivacaine in Infraorbital Nerve Block for Perioperative Analgesia in Paediatric Patients for Cleft Lip Surgery
Phase 3
Completed
- Conditions
- Interventions
- First Posted Date
- 2022-11-21
- Last Posted Date
- 2023-05-15
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 75
- Registration Number
- NCT05624151
- Locations
- 🇪🇬
Ain Shams University hospitals, Cairo, Egypt
Phrenic Nerve Infiltration in Neck Pain
Phase 4
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2022-11-04
- Last Posted Date
- 2024-12-11
- Lead Sponsor
- University of Seville
- Target Recruit Count
- 60
- Registration Number
- NCT05605639
- Locations
- 🇪🇸
Nacho Navarro Fisioterapia, Dos Hermanas, Seville, Spain
🇪🇸Crux Roxa, Seville, Spain
Dexametomedine Versus Ketamine as an Adjuvant in Erector Spinae Block for Perioperative Thoracotomy Pain Control
Phase 4
Completed
- Conditions
- Interventions
- First Posted Date
- 2022-09-23
- Last Posted Date
- 2024-04-18
- Lead Sponsor
- Kasr El Aini Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT05552391
- Locations
- 🇪🇬
Kasralainy Faculty of Medicine, Cairo, Egypt
Effect of Intrathecal Dexamethasone on Intra-operative Hemodynamic in Elderly Patients Undergoing Urologic Endoscopic Surgery
Phase 4
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2022-09-22
- Last Posted Date
- 2022-09-30
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT05549895
ED90 of Epidural Bupivacaine With Lidocaine for the Initiation of Labor Analgesia
- First Posted Date
- 2022-09-16
- Last Posted Date
- 2023-02-08
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT05543694
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Dexamethasone as Adjuvant to Bupivacaine in Suprazygomatic Maxillary Nerve Block
Not Applicable
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2022-09-07
- Last Posted Date
- 2023-02-22
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 34
- Registration Number
- NCT05530811
Comparison Between the Quadratus Lumborum Block ,Erector Spinae Plane Block in Lower Abdominal Surgery
Not Applicable
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2022-09-01
- Last Posted Date
- 2022-10-13
- Lead Sponsor
- Fayoum University Hospital
- Target Recruit Count
- 48
- Registration Number
- NCT05524038
- Locations
- 🇪🇬
Fayoum University hospital, Al Fayyūm, Fayoum Governorate, Egypt
Drug Development Updates
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