Felodipine
- Generic Name
- Felodipine
- Brand Names
- Plendil
- Drug Type
- Small Molecule
- Chemical Formula
- C18H19Cl2NO4
- CAS Number
- 72509-76-3
- Unique Ingredient Identifier
- OL961R6O2C
- Background
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felod...
- Indication
For the treatment of mild to moderate essential hypertension.
- Associated Conditions
- Hypertension
- Associated Therapies
- -
Copenhagen Acute Renal Complications After Transplantations Study Group
- Conditions
- Interventions
- First Posted Date
- 2016-04-20
- Last Posted Date
- 2016-10-06
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 42
- Registration Number
- NCT02744872
- Locations
- 🇩🇰
Department of Nephrology P, Copenhagen University Hospital, Rigshospitalet, Copenhagen Ø, Copenhagen, Denmark
Bioequivalence Study of Felodipine ER Tablets 10 mg Under Fasting Conditions
- First Posted Date
- 2014-12-30
- Last Posted Date
- 2014-12-30
- Lead Sponsor
- Ranbaxy Laboratories Limited
- Target Recruit Count
- 48
- Registration Number
- NCT02327247
Bioequivalence Study of Felodipine ER Tablets 10 mg Under Fed Conditions
- First Posted Date
- 2014-12-08
- Last Posted Date
- 2014-12-08
- Lead Sponsor
- Ranbaxy Laboratories Limited
- Target Recruit Count
- 80
- Registration Number
- NCT02311530
Coffee Interaction With the Antihypertensive Drug Felodipine
- Conditions
- Interventions
- First Posted Date
- 2014-09-05
- Last Posted Date
- 2018-08-13
- Lead Sponsor
- Lawson Health Research Institute
- Target Recruit Count
- 13
- Registration Number
- NCT02232269
- Locations
- 🇨🇦
Victoria Clinical Trials Centre, London, Ontario, Canada
Felodipine Event Reduction Study
- First Posted Date
- 2010-06-04
- Last Posted Date
- 2010-06-25
- Lead Sponsor
- Chinese Academy of Medical Sciences
- Target Recruit Count
- 9800
- Registration Number
- NCT01136863
- Locations
- 🇨🇳
Fu Wai Hospital, Beijing, China
Evaluation of the Pharmacokinetic Interaction Between Candesartan and Felodipine After Ingestion of a Specific Meal
- Conditions
- Interventions
- First Posted Date
- 2009-05-20
- Last Posted Date
- 2010-12-07
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 36
- Registration Number
- NCT00905333
- Locations
- 🇧🇷
Research Site, Americana, Brazil
Role of AT1-receptor Blockers in Insulin-induced Vasodilation.
- Conditions
- Interventions
- First Posted Date
- 2008-08-27
- Last Posted Date
- 2011-03-17
- Lead Sponsor
- Maastricht University Medical Center
- Target Recruit Count
- 32
- Registration Number
- NCT00742066
- Locations
- 🇳🇱
University Hospital Maastricht, Maastricht, P.O. Box 5800, Netherlands
Candesartan Effectiveness Study in Pro-B Type Natriuretic Peptides (BNP)
- Conditions
- Interventions
- First Posted Date
- 2006-07-06
- Last Posted Date
- 2012-04-02
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 315
- Registration Number
- NCT00348686
- Locations
- 🇰🇷
Research Site, Ulsan, Korea, Republic of
Drug Development Updates
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