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Citric acid

Generic Name
Citric acid
Brand Names
Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, As 3, Citrasate, Clenpiq, Cpda-1 Blood Collection System, Cytra-K, EnLyte, Hemosate Ultra, Leukotrap, Oracit, Phexxi, Pico-salax, Picoflo, Purg-odan, Renacidin
Drug Type
Small Molecule
Chemical Formula
C6H8O7
CAS Number
77-92-9
Unique Ingredient Identifier
XF417D3PSL

Overview

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative.

Background

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative.

Indication

No indication information available.

Associated Conditions

  • Acidosis
  • Catheter site calcification caused by appetite
  • Catheter site calcification caused by struvite
  • Gout
  • Headache
  • Heartburn
  • Kidney Stones
  • Metabolic Acidosis

FDA Approved Products

Sterile Cord Blood Collection Unit
Manufacturer:Medsep Corporation
Route:INTRAVENOUS
Strength:0.114 g in 35 mL
Approved: 2011/03/09
NDC:62646-791
ACD-A
Manufacturer:Fenwal, Inc.
Route:INTRAVENOUS
Strength:7.3 g in 1000 mL
Approved: 2022/02/11
NDC:0942-0641
Sodium Citrate and Citric Acid
Manufacturer:ATLANTIC BIOLOGICALS CORP.
Route:ORAL
Strength:334 mg in 5 mL
Approved: 2022/08/15
NDC:17856-0595
Sodium Citrate and Citric Acid
Manufacturer:Pharmaceutical Associates, Inc.
Route:ORAL
Strength:334 mg in 5 mL
Approved: 2022/12/15
NDC:0121-0595
ACD-A
Manufacturer:Fenwal, Inc.
Route:INTRAVENOUS
Strength:3.65 g in 500 mL
Approved: 2022/02/11
NDC:0942-0641

Singapore Approved Products

POTCIT MIXTURE
Manufacturer:BEACONS PHARMACEUTICALS PTE LTD
Form:SOLUTION
Strength:200 mg/5 ml
Online:Yes
Approved: 1990/10/16
Approval:SIN05148P
POTASSIUM CITRATE MIXTURE BP
Manufacturer:ICM PHARMA PTE. LTD.
Form:SOLUTION
Strength:5% w/v
Online:Yes
Approved: 1991/12/19
Approval:SIN06732P
ALKA-SELTZER TABLET (Lemon Flavour)
Manufacturer:BAYER DE MEXICO SA DE CV
Form:TABLET
Strength:1223 mg
Online:Yes
Approved: 1996/04/04
Approval:SIN08632P
E-Z-GAS II GRANULES
Manufacturer:Tower Laboratories
Form:GRANULE
Strength:1.54 g/4 g
Online:Yes
Approved: 1991/07/11
Approval:SIN06442P
PICOPREP Powder for Oral Solution
Manufacturer:Ferring Pharmaceuticals (China) Co., Ltd.
Form:POWDER, FOR SOLUTION
Strength:12 g
Online:Yes
Approved: 2013/01/30
Approval:SIN14303P

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