Olaratumab (IMC-3G3) is a fully human IgG1 monoclonal antibody with antitumor activity that selectively binds the external domain of human platelet-derived growth factor receptor (PDGFR)-α with high affinity and blocks ligand binding. It is composed of two heavy chain molecule fragments and 2 light chain fragments. Studies show that the treatment of olaratum...
用于治疗软组织肉瘤。
UCLA Medical Center, Los Angeles, California, United States
Northwestern University, Chicago, Illinois, United States
Washington University Medical Center, Saint Louis, Missouri, United States
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