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Ronacaleret is a calcium-sensing receptor antagonist.
Ronacaleret is a calcium-sensing receptor antagonist.
751689 is novel small molecules that work by antagonizing calcium-sensing receptors on the surface of the parathyroid gland, thereby triggering a transient release of the body's own stores of parathyroid hormone (PTH). This release of PTH may have the potential to rebuild the bone mass lost as a result of osteoporosis and improve overall bone microarchitecture in these patients.
Post-menopausal women with osteoporosis
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