Thrombin
- Generic Name
- Thrombin
- Brand Names
- Thrombin-jmi
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- -
- Unique Ingredient Identifier
- 25ADE2236L
- Background
Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot.
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- Indication
Bovine thrombin is a topical thrombin indicated to aid hemostasis whenever oozing blood and minor bleeding from capillaries and small venules is accessible and control of bleeding by standard surgical techniques (like suture, ligature, or cautery) is ineffective or impractical . Additionally, topical bovine thrombin can also be used in combination with an ab...
- Associated Conditions
- Refractory to surgical techniques Bleeding
- Associated Therapies
- Tissue Adhesions
A Prospective, Randomized Trial of Histoacryl Injection Versus Thrombin in the Control of Acute Gastric Variceal Bleeding
- Conditions
- Interventions
- First Posted Date
- 2012-10-30
- Last Posted Date
- 2012-11-06
- Lead Sponsor
- National Science Council, Taiwan
- Target Recruit Count
- 62
- Registration Number
- NCT01717612
- Locations
- 🇨🇳
E-DA Hospital, Kaohsiung, Taiwan
Trial Comparing Outcomes With Merocel Packing or Thrombin-JMI for Anterior Epistaxis
- First Posted Date
- 2008-12-24
- Last Posted Date
- 2016-01-15
- Lead Sponsor
- University of Kansas Medical Center
- Target Recruit Count
- 1
- Registration Number
- NCT00814333
- Locations
- 🇺🇸
University of Kansas Medical Center, Kansas City, Kansas, United States
Drug Development Updates
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