MedPath

Fluorometholone

Generic Name
Fluorometholone
Brand Names
FML, FML Forte Liquifilm, FML-S, Flarex, Fluor-OP
Drug Type
Small Molecule
Chemical Formula
C22H29FO4
CAS Number
426-13-1
Unique Ingredient Identifier
SV0CSG527L
Background

A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)

Indication

For the ophthalmic treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

Associated Conditions
Allergic Conjunctivitis (AC), Anterior chamber inflammation, Inflammation, Keratitis, Ocular Inflammation, Ocular bacterial infections

Fluorometholone as Ancillary Therapy for TT Surgery

Not Applicable
Completed
Conditions
Trichiasis
Bilamellar Tarsal Rotation
Trachoma
Interventions
Other: Artificial tears (Placebo)
First Posted Date
2013-09-24
Last Posted Date
2016-04-21
Lead Sponsor
University of Pennsylvania
Target Recruit Count
154
Registration Number
NCT01949454
Locations
🇪🇹

Grarbet Tehadiso Mahber (Grarbet Hospital), Butajira, Snnpr, Ethiopia

Comparison of Two Steroid Regimens to Prevent Transplant Rejection After Corneal Transplant (DMEK)

Phase 2
Completed
Conditions
Bullous Keratopathy
Fuchs' Dystrophy
Interventions
First Posted Date
2011-10-07
Last Posted Date
2014-09-03
Lead Sponsor
Price Vision Group
Target Recruit Count
264
Registration Number
NCT01448213
Locations
🇺🇸

Price Vision Group, Indianapolis, Indiana, United States

🇩🇪

University of Erlangen, Erlangen, Germany

Randomized Controlled Trial of Subconjunctival Bevacizumab Injection in Impending Recurrent Pterygium

Not Applicable
Completed
Conditions
Pterygium of the Conjunctiva and Cornea
Interventions
First Posted Date
2011-02-02
Last Posted Date
2011-02-02
Lead Sponsor
Ramathibodi Hospital
Target Recruit Count
80
Registration Number
NCT01288404
Locations
🇹🇭

Ramathibodi Hospital, Bangkok, Thailand

Topical Cyclosporine vs. Placebo for Epiphora Associated With Docetaxel

Phase 2
Withdrawn
Conditions
Epiphora
Interventions
First Posted Date
2009-01-19
Last Posted Date
2012-08-02
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT00824811

Usefulness of Topical Non-Steroidal Anti-Inflammatory Drugs or Steroids Before Trabeculectomy and Clinical Outcomes

Phase 3
Completed
Conditions
Glaucoma
Trabeculectomy
Fibrosis
Intraocular Pressure
Interventions
Drug: artificial lacrimal tears
First Posted Date
2008-06-30
Last Posted Date
2009-05-29
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Target Recruit Count
62
Registration Number
NCT00707421
Locations
🇧🇪

University Hospitals Leuven, Leuven, Belgium

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