Hypromellose
- Generic Name
- Hypromellose
- Brand Names
- Bion Tears, Clear Eyes Complete, Genteal, Genteal Tears, Genteal Tears Mild, Gonak, Goniovisc, Isopto Alkaline, Nature's Tears, Systane, Tears Lubricant, Tears Naturale, Tears Renewed
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 9004-65-3
- Unique Ingredient Identifier
- 3NXW29V3WO
- Background
Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It is a common...
- Indication
Used as an ophthalmic protectant and lubricant, in artificial tears, and as a diagnostic aid (contact lens procedures; gonioscopy).
- Associated Conditions
- Dry Eyes, Ocular Discomfort, Ocular Irritation
- Associated Therapies
- -
Bilateral, Masked Comparison of PEG-400 Based Artificial Tear and Systane for the Treatment of Dry Eye Signs, Symptoms and Visual Quality
- First Posted Date
- 2008-02-22
- Last Posted Date
- 2010-02-03
- Lead Sponsor
- Bp Consulting, Inc
- Target Recruit Count
- 70
- Registration Number
- NCT00622037
- Locations
- 🇺🇸
Florida Microsurgical Eye Institute, Boynton Beach, Florida, United States
Artificial Tears Study in Mild to Moderate Dry Eye Patients
- Conditions
- Interventions
- First Posted Date
- 2008-02-06
- Last Posted Date
- 2008-02-06
- Lead Sponsor
- Abbott Medical Optics
- Target Recruit Count
- 110
- Registration Number
- NCT00607776
Evaluation of Blood as a Submucosal Cushion During Endoscopic Polypectomy and Mucosal Resection
- Conditions
- Interventions
- First Posted Date
- 2007-12-31
- Last Posted Date
- 2017-09-13
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 18
- Registration Number
- NCT00583466
- Locations
- 🇺🇸
Johns Hopkins Hospital, Baltimore, Maryland, United States
Evaluation of Blink Tears and Systane Concomitant With Restasis for the Treatment of Dry Eye Symptoms
- Conditions
- Interventions
- First Posted Date
- 2007-11-30
- Last Posted Date
- 2018-11-07
- Lead Sponsor
- Medical University of South Carolina
- Target Recruit Count
- 20
- Registration Number
- NCT00565669
- Locations
- 🇺🇸
Medical University of South Carolina, Storm Eye Institute, Charleston, South Carolina, United States
Drug Development Updates
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