Polyethylene glycol

Generic Name
Polyethylene glycol
Brand Names
Bi-peglyte, Clearlax, Colyte, Gavilax, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Gentlelax, Gialax, Glycolax, Golytely, Healthylax, Miralax, Moviprep, Nulytely, Peglyte, Pegylax, Plenvu, Purelax, Suflave
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
25322-68-3
Unique Ingredient Identifier
3WJQ0SDW1A
Background

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary by time of the polymerization process and the...

Indication

Polyethylene glycol is indicated for use as an over-the-counter osmotic laxative to relieve occasional constipation. When used in combination with sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride and potassium chloride, it is used for cleansing of the colon in preparation for colonoscopy in adults.

Associated Conditions
Chronic Constipation, Constipation, Dry Eye Syndrome (DES), Dry Eyes, Occasional Constipation
Associated Therapies
Bowel preparation therapy, Eye lubrication

Comparative Study on the Efficacy of Vibrabot Capsule and Polyethylene Glycol for Chronic Functional Constipation

First Posted Date
2024-04-15
Last Posted Date
2024-04-15
Lead Sponsor
Beijing Tsinghua Chang Gung Hospital
Target Recruit Count
45
Registration Number
NCT06364111
Locations
🇨🇳

XuanJiang, Beijing, Beijing, China

Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic Surgery

First Posted Date
2023-12-07
Last Posted Date
2024-10-08
Lead Sponsor
University Hospitals Cleveland Medical Center
Target Recruit Count
74
Registration Number
NCT06159777
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States

Polyethylene-glycol Assisted Nerve Repair in Phalloplasty

First Posted Date
2023-06-09
Last Posted Date
2024-10-02
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
30
Registration Number
NCT05897086
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Preop Laxatives in Robotic Urologic Surgery

First Posted Date
2023-04-10
Last Posted Date
2023-12-26
Lead Sponsor
Chad R. Tracy
Target Recruit Count
240
Registration Number
NCT05805436
Locations
🇺🇸

University of Iowa Hospitals & Clinics, Iowa City, Iowa, United States

Lactulose vs. Polyethylene Glycol as Bowel Preparation for Colonoscopy in Adults

First Posted Date
2023-02-13
Last Posted Date
2023-12-27
Lead Sponsor
Hospital de Clínicas Dr. Manuel Quintela
Target Recruit Count
150
Registration Number
NCT05726344
Locations
🇺🇾

Hospital de Clinicas, Montevideo, Uruguay

Bowel Preparation Regimen for Colon Capsule Endoscopy Procedure

First Posted Date
2023-02-13
Last Posted Date
2024-02-28
Lead Sponsor
Region Skane
Target Recruit Count
147
Registration Number
NCT05726097
Locations
🇸🇪

Skåne University Hospital, Malmö, Sweden

Comparison of Oral Lactulose Versus Polyethylene Glycol for Bowel Preparation in Low-risk Patients

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2022-12-13
Last Posted Date
2022-12-13
Lead Sponsor
Zhang Xiaofeng,MD
Target Recruit Count
255
Registration Number
NCT05648318
Locations
🇨🇳

Hangzhou first people's Hospital, Hangzhou, Zhejiang, China

Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial

First Posted Date
2022-04-22
Last Posted Date
2023-07-25
Lead Sponsor
All India Institute of Medical Sciences, Bhubaneswar
Target Recruit Count
144
Registration Number
NCT05341180
Locations
🇮🇳

All India Institute of Medical Sciences, Bhubaneswar, Odisha, India

Bladder and Bowel Dysfunction in Children

First Posted Date
2022-04-08
Last Posted Date
2024-05-08
Lead Sponsor
University of Aarhus
Target Recruit Count
100
Registration Number
NCT05318365
Locations
🇩🇰

Goedstrup Regional Hospital, Herning, Denmark

🇩🇰

Aarhus University Hospital, Aarhus, Denmark

🇩🇰

Aalborg University Hospital, Aalborg, Denmark

Comparison of Potassium Binders in the ER

First Posted Date
2020-10-14
Last Posted Date
2024-08-12
Lead Sponsor
University of California, Irvine
Target Recruit Count
120
Registration Number
NCT04585542
Locations
🇺🇸

University of California, Irvine Medical Center, Orange, California, United States

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