Diazepam

Generic Name
Diazepam
Brand Names
Diastat, Valium, Valtoco 5 Mg Dose Kit
Drug Type
Small Molecule
Chemical Formula
C16H13ClN2O
CAS Number
439-14-5
Unique Ingredient Identifier
Q3JTX2Q7TU
Background

A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an an...

Indication

In general, diazepam is useful in the symptomatic management of mild to moderate degrees of anxiety in conditions dominated by tension, excitation, agitation, fear, or aggressiveness such as may occur in psychoneurosis, anxiety reactions due to stress conditions, and anxiety states with somatic expression.
...

Associated Conditions
Acute Agitation, Alcohol Withdrawal Delirium, Alcohol Withdrawal Hallucinosis, Anxiety, Anxiety Disorders, Apprehension, Refractory Epilepsy, Skeletal Muscle Spasms, Status Epilepticus, Stress (Psychology), Tension, Tremor, Convulsive disorders, Intermittent distinct from a patient’s usual seizure pattern, stereotypic episode Epileptic seizure
Associated Therapies
Sedation, Perioperative management therapy

Comparing the Effect of Melatonin, Diazepam, and Placebo on Decreasing the Level of Anxiety Preoperatively

First Posted Date
2023-10-26
Last Posted Date
2023-10-27
Lead Sponsor
University of Jordan
Target Recruit Count
87
Registration Number
NCT06103188
Locations
🇯🇴

Jordan University Hospital, Amman, Jordan

Intermittent Levetricetam in Treatment of Febrile Convulsions

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-05-16
Last Posted Date
2023-05-16
Lead Sponsor
Assiut University
Target Recruit Count
100
Registration Number
NCT05860153

Diazepam Trial in GAD65 Associated Epilepsy

First Posted Date
2022-05-04
Last Posted Date
2024-03-28
Lead Sponsor
Mayo Clinic
Target Recruit Count
30
Registration Number
NCT05361447
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Diazepam and Blood Pressure Regulation

Early Phase 1
Completed
Conditions
Interventions
First Posted Date
2021-10-06
Last Posted Date
2021-10-06
Lead Sponsor
University of Brasilia
Target Recruit Count
40
Registration Number
NCT05069779
Locations
🇧🇷

University of Brasilia, Brasília, DF, Brazil

Remote Treatment of Alcohol Withdrawal

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2021-04-26
Last Posted Date
2024-02-13
Lead Sponsor
Centre for Addiction and Mental Health
Target Recruit Count
30
Registration Number
NCT04858490
Locations
🇨🇦

Centre for Addiction and Mental Health, Toronto, Ontario, Canada

Impact of Placement of a Diazepam Suppository on Early Postoperative Pain Following Pelvic Reconstructive Surgery

First Posted Date
2019-12-13
Last Posted Date
2020-07-23
Lead Sponsor
TriHealth Inc.
Target Recruit Count
130
Registration Number
NCT04198233
Locations
🇺🇸

Trihealth (Good Samaritan Hospital, Bethesda North Hospital), Cincinnati, Ohio, United States

Nonopioid Analgesia After Labral Surgery

First Posted Date
2019-01-31
Last Posted Date
2019-01-31
Lead Sponsor
Henry Ford Health System
Target Recruit Count
100
Registration Number
NCT03825809
Locations
🇺🇸

Henry Ford Health System, Detroit, Michigan, United States

Nonopioid Analgesia After Arthroscopic Meniscus Surgery

First Posted Date
2019-01-29
Last Posted Date
2023-12-05
Lead Sponsor
Henry Ford Health System
Target Recruit Count
61
Registration Number
NCT03820193
Locations
🇺🇸

Henry Ford Health System, Detroit, Michigan, United States

Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction

First Posted Date
2019-01-28
Last Posted Date
2021-02-11
Lead Sponsor
Henry Ford Health System
Target Recruit Count
62
Registration Number
NCT03818932
Locations
🇺🇸

Henry Ford Health System, Detroit, Michigan, United States

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