Diazepam

Generic Name: Diazepam

Brand Names: Diastat, Valium, Valtoco 5 Mg Dose Kit

Drug Type: Small Molecule

Chemical Formula: C_₁₆H_₁₃ClN_₂O

CAS Number: 439-14-5

Unique Ingredient Identifier: Q3JTX2Q7TU

Background: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an an...

Indication: In general, diazepam is useful in the symptomatic management of mild to moderate degrees of anxiety in conditions dominated by tension, excitation, agitation, fear, or aggressiveness such as may occur in psychoneurosis, anxiety reactions due to stress conditions, and anxiety states with somatic expression.
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Associated Conditions: Acute Agitation, Alcohol Withdrawal Delirium, Alcohol Withdrawal Hallucinosis, Anxiety, Anxiety Disorders, Apprehension, Refractory Epilepsy, Skeletal Muscle Spasms, Status Epilepticus, Stress (Psychology), Tension, Tremor, Convulsive disorders, Intermittent distinct from a patient’s usual seizure pattern, stereotypic episode Epileptic seizure

Associated Therapies: Sedation, Perioperative management therapy

Clinical Trials

Anxiety Disorders and Depression Treatment Market to Reach

The Anxiety Disorders and Depression Treatment Market was valued at USD 12.2 billion in 2023 and is projected to reach USD 16.65 billion by 2032, growing at a CAGR of 3.53%. This growth is driven by the rising prevalence of anxiety disorders and depression, advancements in pharmaceutical therapies, and increased awareness and destigmatization of mental health issues.

drugs.com

2 months ago

Are Stroke Survivors Getting Too Many Sedatives Like Xanax, Valium?

A study warns doctors may be overprescribing benzodiazepines like Xanax and Valium to stroke survivors, often for longer than a week, potentially hindering recovery and increasing addiction risk. Researchers analyzed Medicare claims data from over 120,000 stroke victims aged 65 and older, finding 5% were prescribed benzodiazepines within 90 days of their stroke, with 75% of prescriptions lasting over seven days. The American Geriatrics Society advises avoiding benzodiazepines in older adults due to risks like cognitive impairment and falls.

uwm.edu

2 months ago

For the first time, a drug developed at UWM enters FDA clinical trials

A compound developed at the Milwaukee Institute for Drug Discovery (MIDD) is set to enter clinical trials at the FDA, aiming to treat depression and Alzheimer's disease. The drug, GL-Damonia, shows promise in restoring brain cell growth in mice, with no toxicity observed. If successful, it could lead to a new treatment option, though the path through FDA trials is challenging and costly.

Diazepam

Anxiety Disorders and Depression Treatment Market to Reach

Are Stroke Survivors Getting Too Many Sedatives Like Xanax, Valium?

For the first time, a drug developed at UWM enters FDA clinical trials

Drug Development Updates