Sunitinib

Generic Name
Sunitinib
Brand Names
Sutent, Sunitinib Accord
Drug Type
Small Molecule
Chemical Formula
C22H27FN4O2
CAS Number
557795-19-4
Unique Ingredient Identifier
V99T50803M
Background

Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). For these purposes, sunitinib is generally available as an orally administered formul...

Indication

Sunitinib is indicated for the following conditions:

Associated Conditions
Gastrointestinal Stromal Tumor (GIST), Renal Cell Carcinoma (RCC), Renal Cell Carcinoma Recurrent, Unresectable, locally advanced Progressive Neuroendocrine Tumors of pancreatic origin, Unresectable, metastatic Progressive Neuroendocrine Tumors of pancreatic origin
Associated Therapies
-

SU011248 In The Treatment Of Patients With Bevacizumab (Avastin)-Refractory Metastatic Renal Cell Carcinoma

Phase 2
Completed
Conditions
Interventions
First Posted Date
2004-08-11
Last Posted Date
2010-01-12
Lead Sponsor
Pfizer
Target Recruit Count
61
Registration Number
NCT00089648
Locations
🇺🇸

Pfizer Investigational Site, Dallas, Texas, United States

Treatment With SU11248 in Patients With Neuroendocrine Tumors

Phase 2
Completed
Conditions
Interventions
First Posted Date
2003-03-24
Last Posted Date
2008-07-21
Lead Sponsor
Pfizer
Target Recruit Count
107
Registration Number
NCT00056693
Locations
🇺🇸

Pfizer Investigational Site, Philadelphia, Pennsylvania, United States

© Copyright 2024. All Rights Reserved by MedPath